A humanized IFN-γ mouse model reveals skin eschar formation, enhanced susceptibility and scrub typhus pathogenesis

• Ryan H. Cho,

  Roles Data curation, Formal analysis, Methodology, Validation, Writing – original draft, Writing – review & editing

  Affiliation Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, Texas, United States of America

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• Lihai Gao,

  Roles Data curation, Formal analysis, Validation, Visualization

  Affiliation Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, Texas, United States of America

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• Hui Wang,

  Roles Data curation, Formal analysis, Validation, Writing – review & editing

  Affiliation Department of Pathology, University of Texas Medical Branch, Galveston, Texas, United States of America

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• Yixuan Zhou,

  Roles Data curation, Formal analysis, Validation, Writing – review & editing

  Affiliation Department of Neurology, University of Texas Medical Branch, Galveston, Texas, United States of America

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• Casey Gonzales,

  Roles Data curation, Formal analysis, Visualization

  Affiliation Department of Pathology, University of Texas Medical Branch, Galveston, Texas, United States of America

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• Dario Villacreses,

  Roles Data curation, Formal analysis

  Affiliation Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, Texas, United States of America

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• Emmett A. Dews,

  Roles Data curation

  Affiliation Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, Texas, United States of America

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• Xiaofei Zhou,

  Roles Data curation, Methodology, Validation

  Affiliation Biocytogen Pharmaceuticals (Beijing) Co., Ltd., Beijing, China

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• Ruili Lv,

  Roles Data curation, Methodology, Validation

  Affiliation Biocytogen Pharmaceuticals (Beijing) Co., Ltd., Beijing, China

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• Hema P. Narra,

  Roles Writing – review & editing

  Affiliation Department of Pathology, University of Texas Medical Branch, Galveston, Texas, United States of America

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• Lynn Soong ,

  Roles Funding acquisition, Methodology, Project administration, Resources, Software, Supervision, Writing – review & editing

  * E-mail: lysoong@utmb.edu (LS); yu2liang@utmb.edu (YL)

  Affiliations Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, Texas, United States of America, Department of Pathology, University of Texas Medical Branch, Galveston, Texas, United States of America, Institute for Human Infections and Immunity, University of Texas Medical Branch, Galveston, Texas, United States of America, Center for Tropical Diseases, University of Texas Medical Branch, Galveston, Texas, United States of America

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• Yuejin Liang

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: lysoong@utmb.edu (LS); yu2liang@utmb.edu (YL)

  Affiliations Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, Texas, United States of America, Institute for Human Infections and Immunity, University of Texas Medical Branch, Galveston, Texas, United States of America, Center for Tropical Diseases, University of Texas Medical Branch, Galveston, Texas, United States of America

  https://orcid.org/0000-0002-9557-1847

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