VapC toxins promote the pathogenesis of Rickettsia heilongjiangensis by cleaving essential RNAs from both Rickettsia and its host

• Yan Liu,

  Roles Funding acquisition, Investigation, Resources, Supervision, Writing – review & editing

  Affiliations Anhui Province Key Laboratory of Zoonoses, Department of Microbiology, School of Basic Medical Sciences, Anhui Medical University, Hefei, China, School of Public Health, Anhui University of Science and Technology, Hefei, China

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• Weiting Zhou,

  Roles Investigation, Methodology, Validation

  Affiliation Anhui Province Key Laboratory of Zoonoses, Department of Microbiology, School of Basic Medical Sciences, Anhui Medical University, Hefei, China

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• Jiaying Zhao,

  Roles Investigation, Methodology, Validation

  Affiliation Anhui Province Key Laboratory of Zoonoses, Department of Microbiology, School of Basic Medical Sciences, Anhui Medical University, Hefei, China

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• Qingyin Shi,

  Roles Methodology

  Affiliation Anhui Province Key Laboratory of Zoonoses, Department of Microbiology, School of Basic Medical Sciences, Anhui Medical University, Hefei, China

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• Yu Xin,

  Roles Investigation, Methodology

  Affiliation Anhui Province Key Laboratory of Zoonoses, Department of Microbiology, School of Basic Medical Sciences, Anhui Medical University, Hefei, China

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• Xuan Ouyang,

  Roles Investigation, Methodology

  Affiliation State Key Laboratory of Pathogen and Biosecurity, Academy of Military Medical Sciences, Beijing, China

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• Yonghui Yu,

  Roles Investigation, Methodology

  Affiliation State Key Laboratory of Pathogen and Biosecurity, Academy of Military Medical Sciences, Beijing, China

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• Jun Jiao,

  Roles Investigation, Methodology

  Affiliation State Key Laboratory of Pathogen and Biosecurity, Academy of Military Medical Sciences, Beijing, China

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• Maozhang He,

  Roles Formal analysis, Writing – review & editing

  Affiliation Anhui Province Key Laboratory of Zoonoses, Department of Microbiology, School of Basic Medical Sciences, Anhui Medical University, Hefei, China

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• Yajun Song ,

  Roles Methodology, Resources, Supervision, Validation, Writing – review & editing

  * E-mail: songyj@bmi.ac.cn (YS); kehan@ahmu.edu.cn (KX)

  Affiliation State Key Laboratory of Pathogen and Biosecurity, Academy of Military Medical Sciences, Beijing, China

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• Kehan Xu

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: songyj@bmi.ac.cn (YS); kehan@ahmu.edu.cn (KX)

  Affiliation Anhui Province Key Laboratory of Zoonoses, Department of Microbiology, School of Basic Medical Sciences, Anhui Medical University, Hefei, China

  https://orcid.org/0000-0002-3880-9337

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