Specific binding of human P[28] rotavirus VP8* protein to blood group ABH antigens on type 1 chains

Yi Zheng; Xiaoman Sun; Yuting Li; Beibei Huang; Yang Chen; Han Zhou; Cuiyan Cao; Wengang Chai; Zhaojun Duan; Dandi Li; Jingyu Yan; Xinmiao Liang

doi:10.1371/journal.ppat.1013298

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Open Access

Peer-reviewed

Research Article

Specific binding of human P[28] rotavirus VP8* protein to blood group ABH antigens on type 1 chains

Yi Zheng ,

Contributed equally to this work with: Yi Zheng, Xiaoman Sun

Roles Data curation, Funding acquisition, Investigation, Visualization, Writing – original draft

Affiliations State Key Laboratory of Phytochemistry and Natural Medicines, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, China, Ganjiang Chinese Medicine Innovation Center, Nanchang, China
⨯
Xiaoman Sun ,

Contributed equally to this work with: Yi Zheng, Xiaoman Sun

Roles Data curation, Formal analysis, Methodology, Resources, Visualization, Writing – original draft

Affiliation National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases (NITFID), NHC Key Laboratory for Medical Virology and Viral Diseases, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China
⨯
Yuting Li,

Roles Data curation, Investigation, Methodology

Affiliation Ganjiang Chinese Medicine Innovation Center, Nanchang, China
⨯
Beibei Huang,

Roles Data curation, Investigation

Affiliation Ganjiang Chinese Medicine Innovation Center, Nanchang, China
⨯
Yang Chen,

Roles Formal analysis, Methodology, Validation

Affiliations State Key Laboratory of Phytochemistry and Natural Medicines, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, China, Ganjiang Chinese Medicine Innovation Center, Nanchang, China
⨯
Han Zhou,

Roles Formal analysis, Validation

Affiliations State Key Laboratory of Phytochemistry and Natural Medicines, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, China, Ganjiang Chinese Medicine Innovation Center, Nanchang, China
⨯
Cuiyan Cao,

Roles Data curation, Formal analysis

Affiliations State Key Laboratory of Phytochemistry and Natural Medicines, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, China, Ganjiang Chinese Medicine Innovation Center, Nanchang, China
⨯
Wengang Chai,

Roles Conceptualization, Formal analysis, Funding acquisition, Project administration, Writing – review & editing

Affiliation Glycosciences Laboratory, Faculty of Medicine, Imperial College London, Hammersmith, London, United Kingdom
⨯
Zhaojun Duan,

Roles Conceptualization, Project administration

Affiliation National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases (NITFID), NHC Key Laboratory for Medical Virology and Viral Diseases, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China
⨯
Dandi Li ,

Roles Project administration, Resources, Supervision, Writing – review & editing

* E-mail: dandili@126.com (DL); yanjingyu@dicp.ac.cn (JY); liangxm@dicp.ac.cn (XL)

Affiliation National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases (NITFID), NHC Key Laboratory for Medical Virology and Viral Diseases, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China
⨯
Jingyu Yan ,

Roles Conceptualization, Funding acquisition, Project administration, Resources, Supervision, Writing – original draft

* E-mail: dandili@126.com (DL); yanjingyu@dicp.ac.cn (JY); liangxm@dicp.ac.cn (XL)

Affiliations State Key Laboratory of Phytochemistry and Natural Medicines, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, China, Ganjiang Chinese Medicine Innovation Center, Nanchang, China

https://orcid.org/0000-0001-7542-2628

⨯
Xinmiao Liang

Roles Funding acquisition, Project administration, Supervision, Writing – review & editing

* E-mail: dandili@126.com (DL); yanjingyu@dicp.ac.cn (JY); liangxm@dicp.ac.cn (XL)

Affiliations State Key Laboratory of Phytochemistry and Natural Medicines, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, China, Ganjiang Chinese Medicine Innovation Center, Nanchang, China
⨯

Specific binding of human P[28] rotavirus VP8* protein to blood group ABH antigens on type 1 chains

Yi Zheng,
Xiaoman Sun,
Yuting Li,
Beibei Huang,
Yang Chen,
Han Zhou,
Cuiyan Cao,
Wengang Chai,
Zhaojun Duan,
Dandi Li

Published: July 21, 2025
https://doi.org/10.1371/journal.ppat.1013298

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