PHD3-VHL axis controls HIV-2 infection through oxygen-dependent hydroxylation and degradation of Vpx

• Kei Miyakawa ,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Supervision, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: keim@niid.go.jp (KM), aryo@niid.go.jp (AR)

  Affiliations AIDS Research Center, National Institute of Infectious Diseases, Japan Institute for Health Security, Tokyo, Japan, Influenza Research Center, National Institute of Infectious Diseases, Japan Institute for Health Security, Tokyo, Japan, Department of Microbiology, Yokohama City University School of Medicine, Yokohama, Japan

  https://orcid.org/0000-0002-2219-6839

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• Kiho Tanaka,

  Roles Data curation, Investigation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Microbiology, Yokohama City University School of Medicine, Yokohama, Japan

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• Yoko Ino,

  Roles Investigation

  Affiliation Advanced Medical Research Center, Yokohama City University, Yokohama, Japan

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• Yayoi Kimura,

  Roles Data curation, Formal analysis, Investigation, Methodology

  Affiliation Advanced Medical Research Center, Yokohama City University, Yokohama, Japan

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• Taichi Kameya,

  Roles Investigation, Methodology

  Affiliations Department of Bioinformatics and Integrative Omics, National Institute of Infectious Diseases, Japan Institute for Health Security, Tokyo, Japan, Life Science Laboratory, Technology and Development Division, Kanto Chemical Co., Inc., Isehara, Japan

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• Fuminori Mizukoshi,

  Roles Investigation, Methodology

  Affiliation Department of Bioinformatics and Integrative Omics, National Institute of Infectious Diseases, Japan Institute for Health Security, Tokyo, Japan

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• Mayuko Nishi,

  Roles Investigation

  Affiliations Department of Microbiology, Yokohama City University School of Medicine, Yokohama, Japan, Department of Bioinformatics and Integrative Omics, National Institute of Infectious Diseases, Japan Institute for Health Security, Tokyo, Japan

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• Masaru Yokoyama,

  Affiliation Department of Bioinformatics and Integrative Omics, National Institute of Infectious Diseases, Japan Institute for Health Security, Tokyo, Japan

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• Jun Nakabayashi,

  Roles Methodology

  Affiliation Institute of Liberal Arts, Institute of Science Tokyo, Ichikawa, Japan

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• Masako Nomaguchi,

  Roles Resources

  Affiliation Department of Microbiology, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan

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• Hironori Sato,

  Roles Methodology

  Affiliation Department of Bioinformatics and Integrative Omics, National Institute of Infectious Diseases, Japan Institute for Health Security, Tokyo, Japan

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• Hirokazu Kimura,

  Roles Resources

  Affiliation Department of Health Science, Graduate School of Health Sciences, Gunma Paz University, Takasaki, Japan

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• Hirofumi Akari,

  Roles Resources

  Affiliation Center for the Evolutionary Origins of Human Behavior, Kyoto University, Inuyama, Japan

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• Tomoyuki Miura,

  Roles Resources

  Affiliation Institute for Life and Medical Sciences, Kyoto University, Kyoto, Japan

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• Akinori Takaoka,

  Roles Resources

  Affiliation Division of Signaling in Cancer and Immunology, Institute for Genetic Medicine, Hokkaido University, Sapporo, Japan

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• Hideki Hasegawa,

  Roles Funding acquisition

  Affiliations Influenza Research Center, National Institute of Infectious Diseases, Japan Institute for Health Security, Tokyo, Japan, Institute for Vaccine Research and Development, Hokkaido University, Sapporo, Japan

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• Tetsuro Matano,

  Roles Resources

  Affiliations AIDS Research Center, National Institute of Infectious Diseases, Japan Institute for Health Security, Tokyo, Japan, Institute of Medical Science, University of Tokyo, Tokyo, Japan

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• Yoji Andrew Minamishima,

  Roles Resources

  Affiliation Department of Biochemistry, Gunma University Graduate School of Medicine, Maebashi, Japan

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•  [ ... ],
• Akihide Ryo

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Methodology, Project administration, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: keim@niid.go.jp (KM), aryo@niid.go.jp (AR)

  Affiliations Department of Microbiology, Yokohama City University School of Medicine, Yokohama, Japan, Department of Bioinformatics and Integrative Omics, National Institute of Infectious Diseases, Japan Institute for Health Security, Tokyo, Japan

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