Trichomonas vaginalis extracellular vesicles activate the NLRP3 inflammasome and TLR3-mediated inflammatory cascades in host cells

• Ching-Yun Huang,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Graduate Institute of Medical Sciences, National Defense Medical Center, Taipei city, Taiwan, Host-Parasite Interactions Laboratory, National Defense Medical Center, Taipei city, Taiwan

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• Shu-Fang Chiu,

  Roles Data curation, Formal analysis, Funding acquisition, Validation

  Affiliations Graduate Institute of Medical Sciences, National Defense Medical Center, Taipei city, Taiwan, Host-Parasite Interactions Laboratory, National Defense Medical Center, Taipei city, Taiwan, Department of Inspection, Taipei City Hospital, Taipei City, Taiwan

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• Lichieh Julie Chu,

  Roles Data curation, Investigation, Methodology, Writing – original draft

  Affiliations Graduate Institute of Biomedical Sciences, Chang Gung University, Taoyuan, Taiwan, Molecular Medicine Research Center, Chang Gung University, Taoyuan, Taiwan, Department of Otolaryngology - Head & Neck Surgery, Chang Gung Memorial Hospital, Linkou, Taoyuan, Taiwan

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• Yuan-Ming Yeh,

  Roles Formal analysis, Methodology, Software

  Affiliation Genomic Medicine Core Laboratory, Chang Gung Memorial Hospital, Taoyuan, Taiwan

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• Po-Jung Huang,

  Roles Data curation, Formal analysis, Methodology

  Affiliations Genomic Medicine Core Laboratory, Chang Gung Memorial Hospital, Taoyuan, Taiwan, Department of Biomedical Sciences, Chang Gung University, Taoyuan, Taiwan

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• Kuo-Lun Lan,

  Roles Methodology

  Affiliation Department of Pathology, Tri-Service General Hospital, National Defense Medical Center, Taipei city, Taiwan

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• Yu-Ling Tsai,

  Roles Methodology

  Affiliation Department of Pathology, Tri-Service General Hospital, National Defense Medical Center, Taipei city, Taiwan

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• Ching-Chun Liu,

  Roles Formal analysis

  Affiliations Host-Parasite Interactions Laboratory, National Defense Medical Center, Taipei city, Taiwan, Graduate Institute of Pathology and Parasitology, National Defense Medical Center, Taipei City, Taiwan

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• Chien-Fu F. Chen,

  Roles Methodology

  Affiliation Graduate Institute of Life Sciences, National Defense Medical Center, Taipei city, Taiwan

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• Wei-Ning Lin,

  Roles Writing – review & editing

  Affiliation Graduate Institute of Biomedical and Pharmaceutical Science, Fu Jen Catholic University, New Taipei City, Taiwan

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• Kuo-Yang Huang

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Project administration, Resources, Supervision, Validation, Writing – original draft, Writing – review & editing

  * E-mail: cguhgy6934@gmail.com

  Affiliations Host-Parasite Interactions Laboratory, National Defense Medical Center, Taipei city, Taiwan, Graduate Institute of Pathology and Parasitology, National Defense Medical Center, Taipei City, Taiwan

  https://orcid.org/0000-0002-4038-1579

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