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Open Access
Peer-reviewed
Research Article
TRIM14 restricts tembusu virus infection through degrading viral NS1 protein and activating type I interferon signaling
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Peng Zhou,
Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Software, Validation, Visualization, Writing – original draft, Writing – review & editing
Affiliations State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China, The Cooperative Innovation Center for Sustainable Pig Production, Wuhan, China, Key Laboratory of Development of Veterinary Diagnostic Products, Ministry of Agriculture and Rural Affairs of the People’s Republic of China, Wuhan, China
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Qingxiang Zhang,
Roles Investigation, Methodology, Software, Validation
Affiliations State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China, The Cooperative Innovation Center for Sustainable Pig Production, Wuhan, China, Key Laboratory of Development of Veterinary Diagnostic Products, Ministry of Agriculture and Rural Affairs of the People’s Republic of China, Wuhan, China
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Yueshan Yang,
Roles Investigation, Methodology, Software, Validation
Affiliations State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China, The Cooperative Innovation Center for Sustainable Pig Production, Wuhan, China, Key Laboratory of Development of Veterinary Diagnostic Products, Ministry of Agriculture and Rural Affairs of the People’s Republic of China, Wuhan, China
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Dan Liu,
Roles Conceptualization, Validation
Affiliation China Institute of Veterinary Drug Control, Beijing, PR China
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Wanrong Wu,
Roles Methodology, Validation
Affiliations State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China, The Cooperative Innovation Center for Sustainable Pig Production, Wuhan, China, Key Laboratory of Development of Veterinary Diagnostic Products, Ministry of Agriculture and Rural Affairs of the People’s Republic of China, Wuhan, China
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Anan Jongkaewwattana,
Roles Writing – original draft
Affiliation Virology and Cell Technology Research Team, National Center for Genetic Engineering and Biotechnology (BIOTEC), National Science and Technology Development Agency (NSTDA), Klong Nueng, Pathum Thani, Thailand
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Hui Jin,
Roles Conceptualization
Affiliations State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China, The Cooperative Innovation Center for Sustainable Pig Production, Wuhan, China, Key Laboratory of Development of Veterinary Diagnostic Products, Ministry of Agriculture and Rural Affairs of the People’s Republic of China, Wuhan, China
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Hongbo Zhou,
Roles Conceptualization, Funding acquisition
Affiliations State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China, The Cooperative Innovation Center for Sustainable Pig Production, Wuhan, China, Key Laboratory of Development of Veterinary Diagnostic Products, Ministry of Agriculture and Rural Affairs of the People’s Republic of China, Wuhan, China
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Rui Luo
Roles Conceptualization, Formal analysis, Funding acquisition, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing
* E-mail: luorui@mail.hzau.edu.cn
Affiliations State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China, The Cooperative Innovation Center for Sustainable Pig Production, Wuhan, China, Key Laboratory of Development of Veterinary Diagnostic Products, Ministry of Agriculture and Rural Affairs of the People’s Republic of China, Wuhan, China
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TRIM14 restricts tembusu virus infection through degrading viral NS1 protein and activating type I interferon signaling
- Peng Zhou,
- Qingxiang Zhang,
- Yueshan Yang,
- Dan Liu,
- Wanrong Wu,
- Anan Jongkaewwattana,
- Hui Jin,
- Hongbo Zhou,
- Rui Luo
- Published: May 28, 2025
- https://doi.org/10.1371/journal.ppat.1013200