Caspase-1-licensed pyroptosis drives dsRNA-mediated necroptosis and dampens host defense against bacterial pneumonia

• Qinyu Luo,

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft

  Affiliation Department of Clinical Research Center, The Children’s Hospital, Zhejiang University School of Medicine, Hangzhou, China

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• Lihua Shen,

  Roles Investigation, Methodology

  Affiliation Department of Clinical Research Center, The Children’s Hospital, Zhejiang University School of Medicine, Hangzhou, China

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• Shiyue Yang,

  Roles Methodology

  Affiliation Department of Anesthesiology, The First Affiliated Hospital of Soochow University, Suzhou, China

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• Yan Zhang,

  Roles Investigation, Methodology

  Affiliation Department of Clinical Research Center, The Children’s Hospital, Zhejiang University School of Medicine, Hangzhou, China

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• Yihang Pan,

  Roles Investigation, Methodology

  Affiliation Department of Clinical Research Center, The Children’s Hospital, Zhejiang University School of Medicine, Hangzhou, China

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• Zehua Wu,

  Roles Investigation, Methodology, Validation

  Affiliation Department of Clinical Research Center, The Children’s Hospital, Zhejiang University School of Medicine, Hangzhou, China

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• Qiang Shu ,

  Roles Project administration, Supervision

  * E-mail: shuqiang@zju.edu.cn (QS); qixingchen@zju.edu.cn (QC)

  Affiliation Department of Clinical Research Center, The Children’s Hospital, Zhejiang University School of Medicine, Hangzhou, China

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• Qixing Chen

  Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – review & editing

  * E-mail: shuqiang@zju.edu.cn (QS); qixingchen@zju.edu.cn (QC)

  Affiliation Department of Clinical Research Center, The Children’s Hospital, Zhejiang University School of Medicine, Hangzhou, China

  https://orcid.org/0000-0002-8435-6447

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