Astrocyte-derived complement C3 facilitated microglial phagocytosis of synapses in Staphylococcus aureus-associated neurocognitive deficits

• Haifang Zhang ,

  Contributed equally to this work with: Haifang Zhang, Qiyuan Jin, Jijie Li

  Roles Funding acquisition, Project administration, Supervision, Writing – review & editing

  * E-mail: qfcong@suda.edu.cn (QC); haifangzhang@suda.edu.cn (HZ)

  Affiliations Department of Clinical Laboratory, The Second Affiliated Hospital of Soochow University, Suzhou, China, MOE Key Laboratory of Geriatric Diseases and Immunology, Soochow University, Suzhou, China

  https://orcid.org/0009-0007-9146-1265

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• Qiyuan Jin ,

  Contributed equally to this work with: Haifang Zhang, Qiyuan Jin, Jijie Li

  Roles Data curation, Formal analysis, Investigation, Writing – original draft

  Affiliation Department of Clinical Laboratory, The Second Affiliated Hospital of Soochow University, Suzhou, China

  ⨯
• Jijie Li ,

  Contributed equally to this work with: Haifang Zhang, Qiyuan Jin, Jijie Li

  Roles Data curation, Formal analysis, Methodology

  Affiliation Department of Clinical Laboratory, The Second Affiliated Hospital of Soochow University, Suzhou, China

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• Jiali Wang,

  Roles Investigation

  Affiliation Institute of Neuroscience and Jiangsu Key Laboratory of Neuropsychiatric Diseases, Soochow University, Suzhou, China

  ⨯
• Mengqi Li,

  Roles Investigation

  Affiliation Institute of Neuroscience and Jiangsu Key Laboratory of Neuropsychiatric Diseases, Soochow University, Suzhou, China

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• Qiao Yin,

  Roles Investigation

  Affiliation Department of Neurology, Clinical Research Center of Neurological Disease, The Second Affiliated Hospital of Soochow University, Suzhou, China

  ⨯
• Qi Li,

  Roles Investigation

  Affiliation Institute of Neuroscience and Jiangsu Key Laboratory of Neuropsychiatric Diseases, Soochow University, Suzhou, China

  ⨯
• Yuwan Qi,

  Roles Investigation

  Affiliation Institute of Neuroscience and Jiangsu Key Laboratory of Neuropsychiatric Diseases, Soochow University, Suzhou, China

  ⨯
• Lingling Feng,

  Roles Data curation, Methodology

  Affiliation Institute of Neuroscience and Jiangsu Key Laboratory of Neuropsychiatric Diseases, Soochow University, Suzhou, China

  ⨯
• Liang Shen,

  Roles Investigation

  Affiliation Institute of Neuroscience and Jiangsu Key Laboratory of Neuropsychiatric Diseases, Soochow University, Suzhou, China

  ⨯
• Yuan Qin,

  Roles Formal analysis

  Affiliation Institute of Neuroscience and Jiangsu Key Laboratory of Neuropsychiatric Diseases, Soochow University, Suzhou, China

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• Qifei Cong

  Roles Funding acquisition, Project administration, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: qfcong@suda.edu.cn (QC); haifangzhang@suda.edu.cn (HZ)

  ¶‡ Lead contact.

  Affiliations MOE Key Laboratory of Geriatric Diseases and Immunology, Soochow University, Suzhou, China, Institute of Neuroscience and Jiangsu Key Laboratory of Neuropsychiatric Diseases, Soochow University, Suzhou, China, Department of Neurology, Clinical Research Center of Neurological Disease, The Second Affiliated Hospital of Soochow University, Suzhou, China, Department of Nephrology, The Second Affiliated Hospital of Soochow University, Suzhou, China

  https://orcid.org/0000-0002-4446-7222

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