A genetically engineered therapeutic lectin inhibits human influenza A virus infection and sustains robust virus-specific CD8 T cell expansion

• Meng Yu,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Medicine Solna, Karolinska Institutet, Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden

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• Ang Lin,

  Roles Conceptualization, Investigation, Methodology, Writing – review & editing

  Affiliation Department of Medicine Solna, Karolinska Institutet, Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden

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• Faezzah Baharom,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Department of Medicine Solna, Karolinska Institutet, Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden

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• Shuijie Li,

  Roles Investigation, Resources, Writing – review & editing

  Affiliation Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden

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• Maureen Legendre,

  Roles Resources, Writing – review & editing

  Affiliation Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, United States of America

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• Evelyn Covés-Datson,

  Roles Resources, Writing – review & editing

  Affiliations Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, United States of America, Department of Microbiology and Immunology, University of Michigan, Ann Arbor, Michigan, United States of America

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• Ebba Sohlberg,

  Roles Resources, Writing – review & editing

  Affiliation Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden

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• Susanne Schlisio,

  Roles Writing – review & editing

  Affiliation Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden

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• Karin Loré,

  Roles Supervision, Writing – review & editing

  Affiliation Department of Medicine Solna, Karolinska Institutet, Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden

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• David M. Markovitz,

  Roles Conceptualization, Supervision, Writing – original draft, Writing – review & editing

  Affiliations Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, United States of America, Programs in Cellular and Molecular Biology, Immunology, and Cancer Biology, University of Michigan, Ann Arbor, Michigan, United States of America

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• Anna Smed-Sörensen

  Roles Conceptualization, Funding acquisition, Project administration, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: anna.smed.sorensen@ki.se

  Affiliation Department of Medicine Solna, Karolinska Institutet, Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden

  https://orcid.org/0000-0001-6966-7039

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