In vivo Dicer-2 interactome during viral infection reveals novel pro and antiviral factors in Drosophila melanogaster

Claire Rousseau; Thomas Morand; Gabrielle Haas; Emilie Lauret; Lauriane Kuhn; Johana Chicher; Philippe Hammann; Carine Meignin

doi:10.1371/journal.ppat.1013093

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Open Access

Peer-reviewed

Research Article

In vivo Dicer-2 interactome during viral infection reveals novel pro and antiviral factors in Drosophila melanogaster

Claire Rousseau,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

Current address: Institute for Virology and Immunobiology, Julius-Maximilians-Universität-Würzburg, Würzburg, Germany

Affiliation Université de Strasbourg, M3i CNRS UPR9022, Strasbourg, France
⨯
Thomas Morand,

Roles Investigation, Validation, Visualization, Writing – review & editing

Affiliation Université de Strasbourg, M3i CNRS UPR9022, Strasbourg, France
⨯
Gabrielle Haas,

Roles Conceptualization, Investigation, Methodology, Validation, Visualization, Writing – review & editing

Affiliation Université de Strasbourg, M3i CNRS UPR9022, Strasbourg, France
⨯
Emilie Lauret,

Roles Investigation

Affiliation Université de Strasbourg, M3i CNRS UPR9022, Strasbourg, France
⨯
Lauriane Kuhn,

Roles Data curation, Formal analysis, Investigation, Visualization, Writing – original draft

Affiliation Plateforme Protéomique Strasbourg-Esplanade, Université de Strasbourg, CNRS UAR1589, Strasbourg, France
⨯
Johana Chicher,

Roles Data curation, Formal analysis, Methodology, Visualization, Writing – original draft

Affiliation Plateforme Protéomique Strasbourg-Esplanade, Université de Strasbourg, CNRS UAR1589, Strasbourg, France
⨯
Philippe Hammann,

Roles Conceptualization, Investigation, Methodology, Resources, Writing – original draft

Affiliation Plateforme Protéomique Strasbourg-Esplanade, Université de Strasbourg, CNRS UAR1589, Strasbourg, France
⨯
Carine Meignin

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

* E-mail: c.meignin@ibmc-cnrs.unistra.fr

Affiliation Université de Strasbourg, M3i CNRS UPR9022, Strasbourg, France

https://orcid.org/0000-0002-6588-9045

⨯

In vivo Dicer-2 interactome during viral infection reveals novel pro and antiviral factors in Drosophila melanogaster

Claire Rousseau,
Thomas Morand,
Gabrielle Haas,
Emilie Lauret,
Lauriane Kuhn,
Johana Chicher,
Philippe Hammann,
Carine Meignin

Published: May 7, 2025
https://doi.org/10.1371/journal.ppat.1013093

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RNA interference
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Ribonucleases
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Protein interactions
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Small interfering RNA
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Drosophila melanogaster
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Viral transmission and infection
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Interaction networks
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Protein domains
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