Vibrio cholerae cytolysin induces pro-inflammatory and death signals through novel TLR assembly

Shraddha Gandhi; Sindhoora Puravankara; Anish Kumar Mondal; Aakanksha Chauhan; Shashi Prakash Yadav; Kausik Chattopadhyay; Arunika Mukhopadhaya

doi:10.1371/journal.ppat.1013033

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Peer-reviewed

Research Article

Vibrio cholerae cytolysin induces pro-inflammatory and death signals through novel TLR assembly

Shraddha Gandhi,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

Affiliation Department of Biological Sciences, Indian Institute of Science Education and Research Mohali, Mohali, Punjab, India
⨯
Sindhoora Puravankara,

Roles Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft

Affiliation Department of Biological Sciences, Indian Institute of Science Education and Research Mohali, Mohali, Punjab, India
⨯
Anish Kumar Mondal,

Roles Resources

Affiliation Department of Biological Sciences, Indian Institute of Science Education and Research Mohali, Mohali, Punjab, India
⨯
Aakanksha Chauhan,

Roles Investigation

Affiliation Department of Biological Sciences, Indian Institute of Science Education and Research Mohali, Mohali, Punjab, India
⨯
Shashi Prakash Yadav,

Roles Methodology

Affiliation Department of Biological Sciences, Indian Institute of Science Education and Research Mohali, Mohali, Punjab, India
⨯
Kausik Chattopadhyay ,

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Project administration, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

* E-mail: kausik@iisermohali.ac.in (KC); arunika@iisermohali.ac.in (AM)

Affiliation Department of Biological Sciences, Indian Institute of Science Education and Research Mohali, Mohali, Punjab, India

https://orcid.org/0000-0001-8529-9475

⨯
Arunika Mukhopadhaya

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Project administration, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

* E-mail: kausik@iisermohali.ac.in (KC); arunika@iisermohali.ac.in (AM)

Affiliation Department of Biological Sciences, Indian Institute of Science Education and Research Mohali, Mohali, Punjab, India
⨯

Vibrio cholerae cytolysin induces pro-inflammatory and death signals through novel TLR assembly

Shraddha Gandhi,
Sindhoora Puravankara,
Anish Kumar Mondal,
Aakanksha Chauhan,
Shashi Prakash Yadav,
Kausik Chattopadhyay,
Arunika Mukhopadhaya

Published: April 4, 2025
https://doi.org/10.1371/journal.ppat.1013033

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Immune receptor signaling
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