GS143, an inhibitor of E3 ligase β-TrCP, reverses HIV-1 latency without activating T cells via unconventional activation of NFκB

• Srijata Sarkar,

  Roles Data curation, Formal analysis, Investigation, Writing – original draft, Writing – review & editing

  Affiliation Center for Advanced Biotechnology and Medicine, Rutgers University, Piscataway, New Jersey, United States of America

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• Yoshifumi Kobayashi,

  Roles Data curation, Investigation, Writing – original draft, Writing – review & editing

  ¤ Current Address: Department of Oral Biology, Rutgers School of Dental Medicine, Newark, New Jersey, United States of America

  Affiliation Department of Pharmacology, Rutgers Robert Wood Johnson Medical School, Piscataway, New Jersey, United States of America

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• Timothy Russnak,

  Roles Data curation, Investigation, Writing – review & editing

  Affiliation Graduate Program in Molecular Genetics and Microbiology, Rutgers School of Graduate Studies, Piscataway, New Jersey, United States of America

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• Jing Shen,

  Roles Investigation, Writing – review & editing

  Affiliations Center for Advanced Biotechnology and Medicine, Rutgers University, Piscataway, New Jersey, United States of America, Department of Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey, United States of America

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• Ronald G. Nahass,

  Roles Resources, Writing – review & editing

  Affiliations IDCare, Hillsborough, New Jersey, United States of America, Department of Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey, United States of America

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• Joseph P. Dougherty,

  Roles Conceptualization, Funding acquisition, Supervision, Writing – original draft, Writing – review & editing

  Affiliation Department of Pharmacology, Rutgers Robert Wood Johnson Medical School, Piscataway, New Jersey, United States of America

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• Céline Gélinas

  Roles Conceptualization, Funding acquisition, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: gelinas@cabm.rutgers.edu

  Affiliations Center for Advanced Biotechnology and Medicine, Rutgers University, Piscataway, New Jersey, United States of America, Department of Biochemistry and Molecular Biology, Robert Wood Johnson Medical School, Rutgers University, Piscataway, New Jersey, United States of America

  https://orcid.org/0000-0002-3947-0478

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