Unidirectional recruitment between MeCP2 and KSHV-encoded LANA revealed by CRISPR/Cas9 recruitment assay

Ido Lavi; Supriya Bhattacharya; Ankita Awase; Ola Orgil; Nir Avital; Guy Journo; Vyacheslav Gurevich; Meir Shamay

doi:10.1371/journal.ppat.1012972

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Open Access

Peer-reviewed

Research Article

Unidirectional recruitment between MeCP2 and KSHV-encoded LANA revealed by CRISPR/Cas9 recruitment assay

Ido Lavi ,

Contributed equally to this work with: Ido Lavi, Supriya Bhattacharya

Roles Conceptualization, Data curation, Formal analysis, Methodology, Resources

Current address: Shamir Research Institute, University of Haifa, Katzrin, Israel

Affiliation Daniella Lee Casper Laboratory in Viral Oncology, Azrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel
⨯
Supriya Bhattacharya ,

Contributed equally to this work with: Ido Lavi, Supriya Bhattacharya

Roles Conceptualization, Data curation, Formal analysis, Methodology, Resources, Writing – review & editing

Affiliation Daniella Lee Casper Laboratory in Viral Oncology, Azrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel
⨯
Ankita Awase,

Roles Data curation, Resources

Affiliation Daniella Lee Casper Laboratory in Viral Oncology, Azrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel
⨯
Ola Orgil,

Roles Resources

Affiliation Daniella Lee Casper Laboratory in Viral Oncology, Azrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel
⨯
Nir Avital,

Roles Resources

Affiliation Daniella Lee Casper Laboratory in Viral Oncology, Azrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel
⨯
Guy Journo ,

Roles Formal analysis

¶Deceased

Affiliation Daniella Lee Casper Laboratory in Viral Oncology, Azrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel
⨯
Vyacheslav Gurevich,

Roles Conceptualization, Methodology, Resources, Writing – review & editing

Affiliation Daniella Lee Casper Laboratory in Viral Oncology, Azrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel
⨯
Meir Shamay

Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Supervision, Visualization, Writing – original draft, Writing – review & editing

* E-mail: meir.shamay@biu.ac.il

Affiliation Daniella Lee Casper Laboratory in Viral Oncology, Azrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel

https://orcid.org/0000-0003-0223-2852

⨯

Unidirectional recruitment between MeCP2 and KSHV-encoded LANA revealed by CRISPR/Cas9 recruitment assay

Ido Lavi,
Supriya Bhattacharya,
Ankita Awase,
Ola Orgil,
Nir Avital,
Guy Journo,
Vyacheslav Gurevich,
Meir Shamay

Published: March 10, 2025
https://doi.org/10.1371/journal.ppat.1012972

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