CCR2 signaling regulates anti-chlamydia T cell immune responses in the airway

Shuaini Yang; Jinxi Yu; Xue Dong; Jiajia Zeng; Lu Tan; Hong Zhang; Ruoyuan Sun; Yuqing Tuo; Jing Yang; Chunxiao Wan; Hong Bai

doi:10.1371/journal.ppat.1012912

Loading metrics

Open Access

Peer-reviewed

Research Article

CCR2 signaling regulates anti-chlamydia T cell immune responses in the airway

Shuaini Yang ,

Contributed equally to this work with: Shuaini Yang, Jinxi Yu

Roles Conceptualization, Data curation, Formal analysis, Visualization, Writing – original draft, Writing – review & editing

Affiliation Key Laboratory of Immune Microenvironment and Disease, Tianjin Institute of Immunology, Department of Immunology, School of Basic Medical Sciences, Tianjin Key Laboratory of Cellular and Molecular Immunology, Tianjin Medical University, Tianjin, China
⨯
Jinxi Yu ,

Contributed equally to this work with: Shuaini Yang, Jinxi Yu

Roles Data curation, Formal analysis, Visualization, Writing – original draft

Affiliation Key Laboratory of Immune Microenvironment and Disease, Tianjin Institute of Immunology, Department of Immunology, School of Basic Medical Sciences, Tianjin Key Laboratory of Cellular and Molecular Immunology, Tianjin Medical University, Tianjin, China
⨯
Xue Dong,

Roles Investigation, Methodology

Affiliation Department of Physical and Rehabilitation Medicine, Tianjin medical University General Hospital, Tianjin, China
⨯
Jiajia Zeng,

Roles Project administration, Resources

Current address: Department of Clinical Laboratory, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China

Affiliation Key Laboratory of Immune Microenvironment and Disease, Tianjin Institute of Immunology, Department of Immunology, School of Basic Medical Sciences, Tianjin Key Laboratory of Cellular and Molecular Immunology, Tianjin Medical University, Tianjin, China
⨯
Lu Tan,

Roles Investigation, Methodology

Affiliation Key Laboratory of Immune Microenvironment and Disease, Tianjin Institute of Immunology, Department of Immunology, School of Basic Medical Sciences, Tianjin Key Laboratory of Cellular and Molecular Immunology, Tianjin Medical University, Tianjin, China
⨯
Hong Zhang,

Roles Investigation, Methodology

Affiliation Key Laboratory of Immune Microenvironment and Disease, Tianjin Institute of Immunology, Department of Immunology, School of Basic Medical Sciences, Tianjin Key Laboratory of Cellular and Molecular Immunology, Tianjin Medical University, Tianjin, China
⨯
Ruoyuan Sun,

Roles Investigation, Methodology

Affiliation Key Laboratory of Immune Microenvironment and Disease, Tianjin Institute of Immunology, Department of Immunology, School of Basic Medical Sciences, Tianjin Key Laboratory of Cellular and Molecular Immunology, Tianjin Medical University, Tianjin, China
⨯
Yuqing Tuo,

Roles Investigation, Methodology

Affiliation Key Laboratory of Immune Microenvironment and Disease, Tianjin Institute of Immunology, Department of Immunology, School of Basic Medical Sciences, Tianjin Key Laboratory of Cellular and Molecular Immunology, Tianjin Medical University, Tianjin, China
⨯
Jing Yang ,

Roles Resources, Supervision, Validation

* E-mail: jingyang@nankai.edu.cn (JY); wcx22226@163.com (CXW); hongbai25@tmu.edu.cn (HB)

Affiliation Tianjin NanKai Hospital, Tianjin Medical University, Tianjin Key Laboratory of Acute Abdomen Disease Associated Organ Injury and ITCWM Repair, Institute of Integrative Medicine for Acute Abdominal Diseases, Tianjin, China
⨯
Chunxiao Wan ,

Roles Project administration, Supervision, Validation

* E-mail: jingyang@nankai.edu.cn (JY); wcx22226@163.com (CXW); hongbai25@tmu.edu.cn (HB)

Affiliation Department of Physical and Rehabilitation Medicine, Tianjin medical University General Hospital, Tianjin, China

https://orcid.org/0009-0003-9978-9995

⨯
Hong Bai

Roles Funding acquisition, Resources, Supervision, Validation

* E-mail: jingyang@nankai.edu.cn (JY); wcx22226@163.com (CXW); hongbai25@tmu.edu.cn (HB)

Affiliation Key Laboratory of Immune Microenvironment and Disease, Tianjin Institute of Immunology, Department of Immunology, School of Basic Medical Sciences, Tianjin Key Laboratory of Cellular and Molecular Immunology, Tianjin Medical University, Tianjin, China
⨯

CCR2 signaling regulates anti-chlamydia T cell immune responses in the airway

Shuaini Yang,
Jinxi Yu,
Xue Dong,
Jiajia Zeng,
Lu Tan,
Hong Zhang,
Ruoyuan Sun,
Yuqing Tuo,
Jing Yang,
Chunxiao Wan

Published: February 4, 2025
https://doi.org/10.1371/journal.ppat.1012912

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Chlamydia infection
Is the Subject Area "Chlamydia infection" applicable to this article?

Thanks for your feedback.
Respiratory infections
Is the Subject Area "Respiratory infections" applicable to this article?

Thanks for your feedback.
Immune response
Is the Subject Area "Immune response" applicable to this article?

Thanks for your feedback.
Lung development
Is the Subject Area "Lung development" applicable to this article?

Thanks for your feedback.
T helper cells
Is the Subject Area "T helper cells" applicable to this article?

Thanks for your feedback.
Pulmonary imaging
Is the Subject Area "Pulmonary imaging" applicable to this article?

Thanks for your feedback.
Inflammation
Is the Subject Area "Inflammation" applicable to this article?

Thanks for your feedback.
Mouse models
Is the Subject Area "Mouse models" applicable to this article?

Thanks for your feedback.