Pseudorabies virus infection triggers pUL46-mediated phosphorylation of connexin-43 and closure of gap junctions to promote intercellular virus spread

• Alexander Tishchenko,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Writing – original draft, Writing – review & editing

  Affiliation Department of Translational Physiology, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium

  ⨯
• Nicolás Romero,

  Roles Conceptualization, Methodology, Writing – review & editing

  Affiliations Department of Translational Physiology, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium, Department of Microbiology, Blavatnik Institute, Harvard Medical School, Boston, Massachusetts, United States of America

  ⨯
• Cliff Van Waesberghe,

  Roles Investigation, Methodology, Resources

  Affiliation Department of Translational Physiology, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium

  ⨯
• Jonas L. Delva,

  Roles Methodology, Resources

  Affiliation Department of Translational Physiology, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium

  ⨯
• Oliver Vickman,

  Roles Methodology, Resources

  Affiliation Department of Microbiology-Immunology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, United States of America

  ⨯
• Gregory A. Smith,

  Roles Resources, Writing – review & editing

  Affiliation Department of Microbiology-Immunology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, United States of America

  ⨯
• Thomas C. Mettenleiter,

  Roles Resources, Writing – review & editing

  Affiliation Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institute, Insel Riems, Germany

  ⨯
• Walter Fuchs,

  Roles Methodology, Resources

  Affiliation Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institute, Insel Riems, Germany

  ⨯
• Barbara G. Klupp,

  Roles Resources, Writing – review & editing

  Affiliation Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institute, Insel Riems, Germany

  ⨯
• Herman W. Favoreel

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: herman.favoreel@ugent.be

  Affiliation Department of Translational Physiology, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium

  https://orcid.org/0000-0003-4993-6857

  ⨯