Rev-RRE activity modulates HIV-1 replication and latency reactivation: Implications for viral persistence and cure strategies

• Godfrey A. Dzhivhuho ,

  Contributed equally to this work with: Godfrey A. Dzhivhuho, Patrick E. H. Jackson

  Roles Data curation, Formal analysis, Investigation, Methodology, Supervision, Writing – original draft

  Affiliations Department of Microbiology, Immunology, and Cancer Biology, School of Medicine, University of Virginia, Charlottesville, Virginia, United States of America, Myles H. Thaler Center for HIV and Human Retrovirus Research, University of Virginia, Charlottesville, Virginia, United States of America

  ⨯
• Patrick E. H. Jackson ,

  Contributed equally to this work with: Godfrey A. Dzhivhuho, Patrick E. H. Jackson

  Roles Formal analysis, Funding acquisition, Investigation, Methodology, Writing – original draft, Writing – review & editing

  Affiliations Myles H. Thaler Center for HIV and Human Retrovirus Research, University of Virginia, Charlottesville, Virginia, United States of America, Division of Infectious Diseases and International Health, Department of Medicine, School of Medicine, University of Virginia, Charlottesville, Virginia, United States of America

  ⨯
• Ethan S. Honeycutt,

  Roles Investigation, Methodology

  Current address: Department of Molecular Biology and Microbiology, Case Western Reserve University, Cleveland, Ohio, USA

  Affiliations Department of Microbiology, Immunology, and Cancer Biology, School of Medicine, University of Virginia, Charlottesville, Virginia, United States of America, Myles H. Thaler Center for HIV and Human Retrovirus Research, University of Virginia, Charlottesville, Virginia, United States of America

  ⨯
• Flavio da Silva Mesquita,

  Roles Investigation, Methodology

  Current address: Virology Program, Harvard University Medical School, Boston, Massachusetts, USA

  Affiliation Department of Microbiology, Immunology, and Cancer Biology, School of Medicine, University of Virginia, Charlottesville, Virginia, United States of America

  ⨯
• Jing Huang,

  Roles Investigation, Methodology

  Affiliation Department of Microbiology, Immunology, and Cancer Biology, School of Medicine, University of Virginia, Charlottesville, Virginia, United States of America

  ⨯
• Marie-Louise Hammarskjold,

  Roles Conceptualization, Formal analysis, Funding acquisition, Project administration, Resources, Supervision, Writing – review & editing

  Affiliations Department of Microbiology, Immunology, and Cancer Biology, School of Medicine, University of Virginia, Charlottesville, Virginia, United States of America, Myles H. Thaler Center for HIV and Human Retrovirus Research, University of Virginia, Charlottesville, Virginia, United States of America

  ⨯
• David Rekosh

  Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Project administration, Resources, Supervision, Writing – review & editing

  * E-mail: dr4u@virginia.edu

  Affiliations Department of Microbiology, Immunology, and Cancer Biology, School of Medicine, University of Virginia, Charlottesville, Virginia, United States of America, Myles H. Thaler Center for HIV and Human Retrovirus Research, University of Virginia, Charlottesville, Virginia, United States of America

  https://orcid.org/0000-0003-3662-4176

  ⨯