Targeting translation initiation yields fast-killing therapeutics against the zoonotic parasite Cryptosporidium parvum

• Meng Li ,

  Contributed equally to this work with: Meng Li, Jigang Yin

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing

  Affiliation State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Key Laboratory for Zoonosis Research of the Ministry of Education, Institute of Zoonosis, and College of Veterinary Medicine, Jilin University, Changchun, Jilin, China

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• Jigang Yin ,

  Contributed equally to this work with: Meng Li, Jigang Yin

  Roles Conceptualization, Funding acquisition, Supervision

  Affiliation State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Key Laboratory for Zoonosis Research of the Ministry of Education, Institute of Zoonosis, and College of Veterinary Medicine, Jilin University, Changchun, Jilin, China

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• Dongqiang Wang,

  Roles Data curation, Formal analysis, Investigation, Methodology, Validation

  Affiliation State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Key Laboratory for Zoonosis Research of the Ministry of Education, Institute of Zoonosis, and College of Veterinary Medicine, Jilin University, Changchun, Jilin, China

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• Beibei Zou,

  Roles Investigation, Methodology

  Affiliation State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Key Laboratory for Zoonosis Research of the Ministry of Education, Institute of Zoonosis, and College of Veterinary Medicine, Jilin University, Changchun, Jilin, China

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• Guan Zhu

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Methodology, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: cryptosporida@gmail.com

  Affiliations State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Key Laboratory for Zoonosis Research of the Ministry of Education, Institute of Zoonosis, and College of Veterinary Medicine, Jilin University, Changchun, Jilin, China, Department of Veterinary Pathobiology, Texas A and M University, College Station, Texas, United States of America

  https://orcid.org/0000-0003-3888-0659

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