Sniffer restricts arboviral brain infections by regulating ROS levels and protecting blood-brain barrier integrity in Drosophila and mosquitoes

Rui Hu; Mengzhu Li; Shulin Chen; Man Wang; Xinjun Tao; Yihan Zhu; Huan Yan; Yuan Liu

doi:10.1371/journal.ppat.1012797

Loading metrics

Open Access

Peer-reviewed

Research Article

Sniffer restricts arboviral brain infections by regulating ROS levels and protecting blood-brain barrier integrity in Drosophila and mosquitoes

Rui Hu ,

Contributed equally to this work with: Rui Hu, Mengzhu Li

Roles Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

Affiliation State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China
⨯
Mengzhu Li ,

Contributed equally to this work with: Rui Hu, Mengzhu Li

Roles Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization

Affiliation State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China
⨯
Shulin Chen,

Roles Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – review & editing

Affiliation State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China
⨯
Man Wang,

Roles Data curation, Validation, Visualization, Writing – review & editing

Affiliation State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China
⨯
Xinjun Tao,

Roles Methodology

Affiliation State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China
⨯
Yihan Zhu,

Roles Methodology

Affiliation State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China
⨯
Huan Yan,

Roles Methodology

Affiliation State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China
⨯
Yuan Liu

Roles Conceptualization, Funding acquisition, Investigation, Supervision, Visualization, Writing – original draft, Writing – review & editing

* E-mail: yuanliu@whu.edu.cn

Affiliation State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China

https://orcid.org/0000-0003-3892-480X

⨯

Sniffer restricts arboviral brain infections by regulating ROS levels and protecting blood-brain barrier integrity in Drosophila and mosquitoes

Rui Hu,
Mengzhu Li,
Shulin Chen,
Man Wang,
Xinjun Tao,
Yihan Zhu,
Huan Yan,
Yuan Liu

Published: December 16, 2024
https://doi.org/10.1371/journal.ppat.1012797

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Mosquitoes
Is the Subject Area "Mosquitoes" applicable to this article?

Thanks for your feedback.
Drosophila melanogaster
Is the Subject Area "Drosophila melanogaster" applicable to this article?

Thanks for your feedback.
Viral load
Is the Subject Area "Viral load" applicable to this article?

Thanks for your feedback.
RNA interference
Is the Subject Area "RNA interference" applicable to this article?

Thanks for your feedback.
Immunofluorescence
Is the Subject Area "Immunofluorescence" applicable to this article?

Thanks for your feedback.
Viral transmission and infection
Is the Subject Area "Viral transmission and infection" applicable to this article?

Thanks for your feedback.
Arboviral infections
Is the Subject Area "Arboviral infections" applicable to this article?

Thanks for your feedback.
Blood-brain barrier
Is the Subject Area "Blood-brain barrier" applicable to this article?

Thanks for your feedback.