Increased NFAT and NFκB signalling contribute to the hyperinflammatory phenotype in response to Aspergillus fumigatus in a mouse model of cystic fibrosis

• Amelia Bercusson ,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

  ¶‡ AB and TJW contributed equally to this work.

  Affiliations Department of Infectious Disease, Faculty of Medicine, Imperial College, London, United Kingdom, Cystic Fibrosis Unit, University Hospital Southampton NHS Foundation Trust, Southampton, United Kingdom

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• Thomas J. Williams ,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

  ¶‡ AB and TJW contributed equally to this work.

  Affiliations Department of Infectious Disease, Faculty of Medicine, Imperial College, London, United Kingdom, Department of Cardiothoracic Transplantation and Mechanical Support, Harefield Hospital, Royal Brompton and Harefield Hospitals, Guy’s and St. Thomas’ NHS Foundation Trust, London, United Kingdom

  https://orcid.org/0000-0002-1201-2944

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• Nicholas J. Simmonds,

  Roles Conceptualization, Supervision, Writing – review & editing

  Affiliations Adult Cystic Fibrosis Centre, Royal Brompton Hospital, London, United Kingdom, National Heart and Lung Institute, Imperial College, London, United Kingdom

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• Eric WFW Alton,

  Roles Conceptualization, Resources, Writing – review & editing

  Affiliation National Heart and Lung Institute, Imperial College, London, United Kingdom

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• Uta Griesenbach,

  Roles Conceptualization, Resources, Writing – review & editing

  Affiliation National Heart and Lung Institute, Imperial College, London, United Kingdom

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• Anand Shah,

  Roles Conceptualization, Supervision, Writing – review & editing

  Affiliations Department of Infectious Disease, Faculty of Medicine, Imperial College, London, United Kingdom, Department of Respiratory Medicine, Royal Brompton and Harefield Hospitals, Guy’s and St. Thomas’ NHS Foundation Trust, London, United Kingdom

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• Adilia Warris,

  Roles Conceptualization, Supervision, Writing – review & editing

  Affiliation Medical Research Council Centre for Medical Mycology, University of Exeter, Exeter, United Kingdom

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• Darius Armstrong-James

  Roles Conceptualization, Funding acquisition, Methodology, Project administration, Supervision, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: d.armstrong@imperial.ac.uk

  Affiliations Department of Infectious Disease, Faculty of Medicine, Imperial College, London, United Kingdom, Department of Respiratory Medicine, Royal Brompton and Harefield Hospitals, Guy’s and St. Thomas’ NHS Foundation Trust, London, United Kingdom

  https://orcid.org/0000-0002-1014-7343

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