Enterococcal cell wall remodelling underpins pathogenesis via the release of the Enteroccocal Polysaccharide Antigen (EPA)

• Robert E. Smith ,

  Contributed equally to this work with: Robert E. Smith, Bartosz J. Michno, Rene L. Christena

  Roles Conceptualization, Data curation, Funding acquisition, Investigation, Methodology, Validation, Visualization, Writing – review & editing

  ¶☯ These authors contributed equally.

  Affiliation Molecular Microbiology, School of Biosciences, University of Sheffield, Sheffield, United Kingdom

  ⨯
• Bartosz J. Michno ,

  Contributed equally to this work with: Robert E. Smith, Bartosz J. Michno, Rene L. Christena

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Resources, Validation, Visualization, Writing – review & editing

  ¶☯ These authors contributed equally.

  Affiliations Department of Evolutionary Immunology, Institute of Zoology and Biomedical Research, Faculty of Biology, Jagiellonian University, Kraków, Poland, Doctoral School of Exact and Natural Sciences, Jagiellonian University, Krakow, Poland

  ⨯
• Rene L. Christena ,

  Contributed equally to this work with: Robert E. Smith, Bartosz J. Michno, Rene L. Christena

  Roles Data curation, Funding acquisition, Investigation, Methodology, Visualization, Writing – review & editing

  ¶☯ These authors contributed equally.

  Affiliation Molecular Microbiology, School of Biosciences, University of Sheffield, Sheffield, United Kingdom

  ⨯
• Finn O’Dea,

  Roles Conceptualization, Data curation, Funding acquisition, Investigation, Methodology, Validation, Visualization, Writing – review & editing

  Affiliation Molecular Microbiology, School of Biosciences, University of Sheffield, Sheffield, United Kingdom

  ⨯
• Jessica L. Davis,

  Roles Conceptualization, Data curation, Funding acquisition, Investigation, Validation, Visualization, Writing – review & editing

  Affiliation Molecular Microbiology, School of Biosciences, University of Sheffield, Sheffield, United Kingdom

  ⨯
• Ian D.E.A. Lidbury,

  Roles Conceptualization, Investigation, Methodology, Visualization, Writing – review & editing

  Affiliation Molecular Microbiology, School of Biosciences, University of Sheffield, Sheffield, United Kingdom

  ⨯
• Marcel G. Alamán-Zárate,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Molecular Microbiology, School of Biosciences, University of Sheffield, Sheffield, United Kingdom

  ⨯
• Danai Stefanidi,

  Roles Investigation, Writing – review & editing

  Affiliation Molecular Microbiology, School of Biosciences, University of Sheffield, Sheffield, United Kingdom

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• Emmanuel Maes,

  Roles Data curation, Investigation, Methodology, Writing – review & editing

  Affiliation University of Lille, CNRS, Inserm, CHU Lille, Institut Pasteur de Lille, Lille, France

  ⨯
• Hannah Fisher,

  Roles Data curation, Investigation, Methodology, Writing – review & editing

  Affiliation Molecular Microbiology, School of Biosciences, University of Sheffield, Sheffield, United Kingdom

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• Tomasz K. Prajsnar,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Writing – review & editing

  Affiliation Department of Evolutionary Immunology, Institute of Zoology and Biomedical Research, Faculty of Biology, Jagiellonian University, Kraków, Poland

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• Stéphane Mesnage

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: s.mesnage@sheffield.ac.uk

  Affiliation Molecular Microbiology, School of Biosciences, University of Sheffield, Sheffield, United Kingdom

  https://orcid.org/0000-0003-1648-4890

  ⨯