Emerging mutation in SARS-CoV-2 facilitates escape from NK cell recognition and associates with enhanced viral fitness

Eleni Bilev; Nicole Wild; Pouria Momayyezi; Benedetta Maria Sala; Renhua Sun; Tatyana Sandalova; Nicole Marquardt; Hans-Gustaf Ljunggren; Adnane Achour; Quirin Hammer

doi:10.1371/journal.ppat.1012755

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Open Access

Peer-reviewed

Research Article

Emerging mutation in SARS-CoV-2 facilitates escape from NK cell recognition and associates with enhanced viral fitness

Eleni Bilev,

Roles Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

Affiliation Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden
⨯
Nicole Wild,

Roles Formal analysis, Investigation, Visualization

Affiliation Center for Hematology and Regenerative Medicine, Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden
⨯
Pouria Momayyezi,

Roles Formal analysis, Investigation, Writing – review & editing

Affiliation Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden
⨯
Benedetta Maria Sala,

Roles Formal analysis, Investigation, Writing – review & editing

Affiliation Science for Life Laboratory, Department of Medicine Solna, Karolinska Institutet & Division of Infectious Diseases, Karolinska University Hospital Solna, Stockholm, Sweden
⨯
Renhua Sun,

Roles Formal analysis, Investigation, Writing – review & editing

Affiliation Science for Life Laboratory, Department of Medicine Solna, Karolinska Institutet & Division of Infectious Diseases, Karolinska University Hospital Solna, Stockholm, Sweden
⨯
Tatyana Sandalova,

Roles Formal analysis, Investigation, Writing – review & editing

Affiliation Science for Life Laboratory, Department of Medicine Solna, Karolinska Institutet & Division of Infectious Diseases, Karolinska University Hospital Solna, Stockholm, Sweden
⨯
Nicole Marquardt,

Roles Funding acquisition, Supervision

Affiliation Center for Hematology and Regenerative Medicine, Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden
⨯
Hans-Gustaf Ljunggren,

Roles Funding acquisition, Writing – review & editing

Affiliation Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden
⨯
Adnane Achour ,

Contributed equally to this work with: Adnane Achour, Quirin Hammer

Roles Funding acquisition, Supervision, Writing – original draft, Writing – review & editing

Affiliation Science for Life Laboratory, Department of Medicine Solna, Karolinska Institutet & Division of Infectious Diseases, Karolinska University Hospital Solna, Stockholm, Sweden
⨯
Quirin Hammer

Contributed equally to this work with: Adnane Achour, Quirin Hammer

Roles Conceptualization, Funding acquisition, Supervision, Writing – original draft, Writing – review & editing

* E-mail: quirin.hammer@ki.se

Affiliation Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden

https://orcid.org/0000-0003-2968-6061

⨯

Emerging mutation in SARS-CoV-2 facilitates escape from NK cell recognition and associates with enhanced viral fitness

Eleni Bilev,
Nicole Wild,
Pouria Momayyezi,
Benedetta Maria Sala,
Renhua Sun,
Tatyana Sandalova,
Nicole Marquardt,
Hans-Gustaf Ljunggren,
Adnane Achour,
Quirin Hammer

Published: December 9, 2024
https://doi.org/10.1371/journal.ppat.1012755

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