Sustained immune activation and impaired epithelial barrier integrity in the ectocervix of women with chronic HIV infection

• Mathias Franzén Boger ,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: Mathias.franzen.boger@ki.se

  Affiliation Division of Infectious Diseases, Department of Medicine Solna, Karolinska Institutet, Karolinska University Hospital, Center for Molecular Medicine, Stockholm, Sweden

  https://orcid.org/0009-0009-0219-3655

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• Tyra Hasselrot,

  Roles Formal analysis, Visualization, Writing – review & editing

  Affiliation Division of Infectious Diseases, Department of Medicine Solna, Karolinska Institutet, Karolinska University Hospital, Center for Molecular Medicine, Stockholm, Sweden

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• Vilde Kaldhusdal,

  Roles Data curation, Formal analysis, Investigation, Software, Validation, Writing – review & editing

  Affiliation Division of Infectious Diseases, Department of Medicine Solna, Karolinska Institutet, Karolinska University Hospital, Center for Molecular Medicine, Stockholm, Sweden

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• Gisele H. B. Miranda,

  Roles Data curation, Formal analysis, Methodology, Software, Writing – review & editing

  Affiliations Division of Computational Science and Technology, KTH Royal Institute of Technology, Stockholm, Sweden, BioImage Informatics Facility, Science for Life Laboratory, Solna, Sweden

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• Paulo Czarnewski,

  Roles Data curation, Formal analysis, Investigation, Methodology, Software, Validation, Visualization, Writing – review & editing

  Affiliation Science for Life Laboratory, Department of Biochemistry and Biophysics and National Bioinformatics Infrastructure Sweden, Stockholm University, Stockholm, Sweden

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• Gabriella Edfeldt,

  Roles Methodology, Software, Writing – review & editing

  Affiliation Division of Infectious Diseases, Department of Medicine Solna, Karolinska Institutet, Karolinska University Hospital, Center for Molecular Medicine, Stockholm, Sweden

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• Frideborg Bradley,

  Roles Data curation, Formal analysis, Methodology, Writing – review & editing

  Affiliation Division of Infectious Diseases, Department of Medicine Solna, Karolinska Institutet, Karolinska University Hospital, Center for Molecular Medicine, Stockholm, Sweden

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• Genta Rexaj,

  Roles Data curation, Methodology, Writing – review & editing

  Affiliation Division of Infectious Diseases, Department of Medicine Solna, Karolinska Institutet, Karolinska University Hospital, Center for Molecular Medicine, Stockholm, Sweden

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• Julie Lajoie,

  Roles Data curation, Investigation, Writing – review & editing

  Affiliation Department of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, Canada

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• Kenneth Omollo,

  Roles Data curation, Investigation, Writing – review & editing

  Affiliation Department of Medical Microbiology and Immunology, University of Nairobi, Nairobi, Kenya

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• Joshua Kimani,

  Roles Conceptualization, Project administration, Resources, Supervision, Writing – review & editing

  Affiliations Department of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, Canada, Department of Medical Microbiology and Immunology, University of Nairobi, Nairobi, Kenya, Partners for Health and Development in Africa, Nairobi, Kenya

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• Keith R. Fowke,

  Roles Conceptualization, Funding acquisition, Project administration, Resources, Supervision, Writing – review & editing

  Affiliations Department of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, Canada, Department of Medical Microbiology and Immunology, University of Nairobi, Nairobi, Kenya, Partners for Health and Development in Africa, Nairobi, Kenya, Department of Community Health Sciences, University of Manitoba, Winnipeg, Canada

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• Kristina Broliden ,

  Roles Conceptualization, Data curation, Funding acquisition, Investigation, Project administration, Resources, Supervision, Validation, Writing – original draft, Writing – review & editing

  ¶‡ These authors are joint senior authors on this work.

  Affiliation Division of Infectious Diseases, Department of Medicine Solna, Karolinska Institutet, Karolinska University Hospital, Center for Molecular Medicine, Stockholm, Sweden

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• Annelie Tjernlund

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Writing – original draft, Writing – review & editing

  ¶‡ These authors are joint senior authors on this work.

  Affiliation Division of Infectious Diseases, Department of Medicine Solna, Karolinska Institutet, Karolinska University Hospital, Center for Molecular Medicine, Stockholm, Sweden

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