ACE2-independent sarbecovirus cell entry can be supported by TMPRSS2-related enzymes and can reduce sensitivity to antibody-mediated neutralization

• Lu Zhang,

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Writing – original draft, Writing – review & editing

  Affiliations Infection Biology Unit, German Primate Center–Leibniz Institute for Primate Research, Göttingen, Germany, Faculty of Biology and Psychology, Georg-August-University Göttingen, Göttingen, Germany

  ⨯
• Hsiu-Hsin Cheng,

  Roles Investigation, Writing – review & editing

  Affiliations Infection Biology Unit, German Primate Center–Leibniz Institute for Primate Research, Göttingen, Germany, Faculty of Biology and Psychology, Georg-August-University Göttingen, Göttingen, Germany

  ⨯
• Nadine Krüger,

  Roles Conceptualization, Formal analysis, Investigation, Writing – review & editing

  Affiliation Platform Infection Models, German Primate Center, Göttingen, Germany

  ⨯
• Bojan Hörnich,

  Roles Investigation, Writing – review & editing

  Affiliation Junior Research Group Herpesviruses, German Primate Center, Göttingen, Germany

  ⨯
• Luise Graichen,

  Roles Investigation, Writing – review & editing

  Affiliations Infection Biology Unit, German Primate Center–Leibniz Institute for Primate Research, Göttingen, Germany, Faculty of Biology and Psychology, Georg-August-University Göttingen, Göttingen, Germany

  ⨯
• Alexander S. Hahn,

  Roles Investigation, Writing – review & editing

  Affiliation Junior Research Group Herpesviruses, German Primate Center, Göttingen, Germany

  ⨯
• Sebastian R. Schulz,

  Roles Resources, Writing – review & editing

  Affiliation Division of Molecular Immunology, Department of Internal Medicine 3, Friedrich-Alexander University of Erlangen-Nürnberg, Erlangen, Germany

  ⨯
• Hans-Martin Jäck,

  Roles Resources, Writing – review & editing

  Affiliation Division of Molecular Immunology, Department of Internal Medicine 3, Friedrich-Alexander University of Erlangen-Nürnberg, Erlangen, Germany

  ⨯
• Metodi V. Stankov,

  Roles Resources, Writing – review & editing

  Affiliation Department of Rheumatology and Immunology, Hannover Medical School, Hannover, Germany

  ⨯
• Georg M. N. Behrens,

  Roles Resources, Writing – review & editing

  Affiliations Department of Rheumatology and Immunology, Hannover Medical School, Hannover, Germany, German Centre for Infection Research (DZIF), partner site Hannover-Braunschweig, Hannover, Germany

  ⨯
• Marcel A. Müller,

  Roles Resources, Writing – review & editing

  Affiliations Institute of Virology, Campus Charité Mitte, Charité—Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany, German Centre for Infection Research (DZIF), partner site Berlin, Berlin, Germany

  ⨯
• Christian Drosten,

  Roles Resources, Writing – review & editing

  Affiliations Institute of Virology, Campus Charité Mitte, Charité—Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany, German Centre for Infection Research (DZIF), partner site Berlin, Berlin, Germany

  ⨯
• Onnen Mörer,

  Roles Resources, Writing – review & editing

  Affiliation Department of Anesthesiology, University of Göttingen Medical Center, Göttingen, Georg-August University of Göttingen, Göttingen, Germany

  ⨯
• Martin Sebastian Winkler,

  Roles Resources, Writing – review & editing

  Affiliation Department of Anesthesiology, University of Göttingen Medical Center, Göttingen, Georg-August University of Göttingen, Göttingen, Germany

  ⨯
• ZhaoHui Qian,

  Roles Resources, Writing – review & editing

  Affiliation NHC Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China

  ⨯
• Stefan Pöhlmann ,

  Roles Conceptualization, Formal analysis, Funding acquisition, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: spoehlmann@dpz.eu (SP); mhoffmann@dpz.eu (MH)

  Affiliations Infection Biology Unit, German Primate Center–Leibniz Institute for Primate Research, Göttingen, Germany, Faculty of Biology and Psychology, Georg-August-University Göttingen, Göttingen, Germany

  https://orcid.org/0000-0001-6086-9136

  ⨯
•  [ ... ],
• Markus Hoffmann

  Roles Conceptualization, Formal analysis, Investigation, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: spoehlmann@dpz.eu (SP); mhoffmann@dpz.eu (MH)

  Affiliations Infection Biology Unit, German Primate Center–Leibniz Institute for Primate Research, Göttingen, Germany, Faculty of Biology and Psychology, Georg-August-University Göttingen, Göttingen, Germany

  https://orcid.org/0000-0003-4603-7696

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