Swine NONO promotes IRF3-mediated antiviral immune response by Detecting PRRSV N protein

Dandan Jiang; Chao Sui; Xiangju Wu; Ping Jiang; Juan Bai; Yue Hu; Xiaoyan Cong; Juntong Li; Dongwan Yoo; Laura C. Miller; Changhee Lee; Yijun Du; Jing Qi

doi:10.1371/journal.ppat.1012622

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Open Access

Peer-reviewed

Research Article

Swine NONO promotes IRF3-mediated antiviral immune response by Detecting PRRSV N protein

Dandan Jiang,

Roles Conceptualization, Investigation, Methodology

Affiliation Shandong Key Laboratory of Animal Disease Control and Breeding/Key Laboratory of Livestock and Poultry Multi-omics of MARA, Institute of Animal Science and Veterinary Medicine, Shandong Academy of Agricultural Sciences, Jinan, Shandong, China
⨯
Chao Sui,

Roles Conceptualization, Investigation, Methodology

Affiliation Laboratory Animal Center, Qilu Hospital of Shandong University, Jinan, Shandong, China
⨯
Xiangju Wu,

Roles Investigation, Methodology

Affiliation Shandong Key Laboratory of Animal Disease Control and Breeding/Key Laboratory of Livestock and Poultry Multi-omics of MARA, Institute of Animal Science and Veterinary Medicine, Shandong Academy of Agricultural Sciences, Jinan, Shandong, China
⨯
Ping Jiang,

Roles Conceptualization, Formal analysis

Affiliation Key Laboratory of Animal Diseases Diagnostic and Immunology, Ministry of Agriculture, MOE International Joint Collaborative Research Laboratory for Animal Health & Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, China
⨯
Juan Bai,

Roles Investigation, Methodology

Affiliation Key Laboratory of Animal Diseases Diagnostic and Immunology, Ministry of Agriculture, MOE International Joint Collaborative Research Laboratory for Animal Health & Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, China
⨯
Yue Hu,

Roles Investigation, Methodology

Affiliation Shandong Key Laboratory of Animal Disease Control and Breeding/Key Laboratory of Livestock and Poultry Multi-omics of MARA, Institute of Animal Science and Veterinary Medicine, Shandong Academy of Agricultural Sciences, Jinan, Shandong, China
⨯
Xiaoyan Cong,

Roles Investigation, Methodology

Affiliation Shandong Key Laboratory of Animal Disease Control and Breeding/Key Laboratory of Livestock and Poultry Multi-omics of MARA, Institute of Animal Science and Veterinary Medicine, Shandong Academy of Agricultural Sciences, Jinan, Shandong, China
⨯
Juntong Li,

Roles Investigation, Methodology

Affiliation Shandong Key Laboratory of Animal Disease Control and Breeding/Key Laboratory of Livestock and Poultry Multi-omics of MARA, Institute of Animal Science and Veterinary Medicine, Shandong Academy of Agricultural Sciences, Jinan, Shandong, China
⨯
Dongwan Yoo,

Roles Conceptualization, Formal analysis

Affiliation Department of Pathobiology, College of Veterinary Medicine, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States of America
⨯
Laura C. Miller,

Roles Conceptualization, Formal analysis

Affiliation Department of Diagnostic Medicine and Pathobiology, College of Veterinary Medicine, Kansas State University, Manhattan, Kansas, United States of America
⨯
Changhee Lee,

Roles Conceptualization, Formal analysis

Affiliation College of Veterinary Medicine and Virus Vaccine Research Center, Gyeongsang National University, Jinju, Republic of Korea
⨯
Yijun Du ,

Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – original draft, Writing – review & editing

* E-mail: duyijun0916@163.com (YD); qj-happy2008@163.com (JQ)

Affiliation Shandong Key Laboratory of Animal Disease Control and Breeding/Key Laboratory of Livestock and Poultry Multi-omics of MARA, Institute of Animal Science and Veterinary Medicine, Shandong Academy of Agricultural Sciences, Jinan, Shandong, China

https://orcid.org/0000-0001-9215-4637

⨯
Jing Qi

Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – original draft, Writing – review & editing

* E-mail: duyijun0916@163.com (YD); qj-happy2008@163.com (JQ)

Affiliation Shandong Key Laboratory of Animal Disease Control and Breeding/Key Laboratory of Livestock and Poultry Multi-omics of MARA, Institute of Animal Science and Veterinary Medicine, Shandong Academy of Agricultural Sciences, Jinan, Shandong, China
⨯

Swine NONO promotes IRF3-mediated antiviral immune response by Detecting PRRSV N protein

Dandan Jiang,
Chao Sui,
Xiangju Wu,
Ping Jiang,
Juan Bai,
Yue Hu,
Xiaoyan Cong,
Juntong Li,
Dongwan Yoo,
Laura C. Miller

Published: October 16, 2024
https://doi.org/10.1371/journal.ppat.1012622

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Immune receptor signaling
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Luciferase
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