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Open Access
Peer-reviewed
Research Article
Pseudorabies Virus UL4 protein promotes the ASC-dependent inflammasome activation and pyroptosis to exacerbate inflammation
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Xiaohua Zhang,
Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Software, Validation, Visualization, Writing – original draft, Writing – review & editing
Affiliation College of Veterinary Medicine, Northwest A&F University, Yangling, China
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Guiyuan Chen,
Roles Data curation, Investigation, Methodology, Visualization, Writing – review & editing
Affiliation College of Veterinary Medicine, Northwest A&F University, Yangling, China
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Junqing Yin,
Roles Methodology, Writing – review & editing
Affiliation College of Veterinary Medicine, Northwest A&F University, Yangling, China
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Lichen Nie,
Roles Methodology
Affiliation College of Veterinary Medicine, Northwest A&F University, Yangling, China
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Linghao Li,
Roles Methodology
Affiliation College of Veterinary Medicine, Northwest A&F University, Yangling, China
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Qian Du,
Roles Data curation, Writing – review & editing
Affiliations College of Veterinary Medicine, Northwest A&F University, Yangling, China, Engineering Research Center of Efficient New Vaccines for Animals, Ministry of Education, Yangling, China, Key Laboratory of Ruminant Disease Prevention and Control (West), Ministry of Agriculture and Rural Affairs, Yangling, China, Engineering Research Center of Efficient New Vaccines for Animals, Universities of Shaanxi Province, Yangling, China
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Dewen Tong ,
Roles Conceptualization, Funding acquisition, Supervision, Writing – review & editing
* E-mail: dwtong@nwsuaf.edu.cn (DT); yonghuang@nwsuaf.edu.cn (YH)
Affiliations College of Veterinary Medicine, Northwest A&F University, Yangling, China, Engineering Research Center of Efficient New Vaccines for Animals, Ministry of Education, Yangling, China, Key Laboratory of Ruminant Disease Prevention and Control (West), Ministry of Agriculture and Rural Affairs, Yangling, China, Engineering Research Center of Efficient New Vaccines for Animals, Universities of Shaanxi Province, Yangling, China
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Yong Huang
Roles Conceptualization, Formal analysis, Funding acquisition, Project administration, Supervision, Writing – review & editing
* E-mail: dwtong@nwsuaf.edu.cn (DT); yonghuang@nwsuaf.edu.cn (YH)
Affiliations College of Veterinary Medicine, Northwest A&F University, Yangling, China, Engineering Research Center of Efficient New Vaccines for Animals, Ministry of Education, Yangling, China, Key Laboratory of Ruminant Disease Prevention and Control (West), Ministry of Agriculture and Rural Affairs, Yangling, China, Engineering Research Center of Efficient New Vaccines for Animals, Universities of Shaanxi Province, Yangling, China
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Pseudorabies Virus UL4 protein promotes the ASC-dependent inflammasome activation and pyroptosis to exacerbate inflammation
- Xiaohua Zhang,
- Guiyuan Chen,
- Junqing Yin,
- Lichen Nie,
- Linghao Li,
- Qian Du,
- Dewen Tong,
- Yong Huang
- Published: September 24, 2024
- https://doi.org/10.1371/journal.ppat.1012546