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Open Access
Peer-reviewed
Research Article
The triglyceride-synthesizing enzyme diacylglycerol acyltransferase 2 modulates the formation of the hepatitis C virus replication organelle
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Isabelle Reichert,
Roles Conceptualization, Data curation, Formal analysis, Investigation, Software, Validation, Visualization, Writing – original draft, Writing – review & editing
Affiliation Leibniz Institute of Virology (LIV), Hamburg, Germany
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Ji-Young Lee,
Roles Formal analysis, Investigation, Validation, Visualization
Affiliations Heidelberg University, Medical Faculty Heidelberg, Department of Infectious Diseases, Molecular Virology, Center for Integrative Infectious Diseases Research, Heidelberg, Germany, German Center for Infection Research (DZIF), partner site Heidelberg, Heidelberg, Germany
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Laura Weber,
Roles Investigation, Methodology, Validation, Writing – review & editing
Affiliation Leibniz Institute of Virology (LIV), Hamburg, Germany
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Marceline M. Fuh,
Roles Investigation, Validation
Affiliation Department of Biochemistry and Molecular Cell Biology, Center for Experimental Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
⨯ - Lina Schlaeger,
- Stefanie Rößler,
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Volker Kinast,
Roles Investigation, Validation, Writing – review & editing
Affiliations Department of Medical Microbiology and Virology, Carl von Ossietzky University Oldenburg, Oldenburg, Germany, Department of Molecular and Medical Virology, Ruhr University Bochum, Bochum, Germany
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Sarah Schlienkamp,
Roles Investigation, Validation
Affiliation Department of Molecular and Medical Virology, Ruhr University Bochum, Bochum, Germany
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Janina Conradi,
Roles Investigation, Validation, Writing – review & editing
Affiliations Leibniz Institute of Virology (LIV), Hamburg, Germany, Integrative Analysis of Pathogen-Induced Compartments, Leibniz ScienceCampus InterACt, Hamburg, Germany
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Florian W. R. Vondran,
Roles Resources
Affiliation ReMediES, Department of General, Visceral and Transplantation Surgery, Hannover Medical School, Hannover, Germany
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Stephanie Pfaender,
Roles Project administration
Affiliations Leibniz Institute of Virology (LIV), Hamburg, Germany, Institute of Virology and Cell Biology, University of Luebeck, Luebeck, Germany
⨯ - Pietro Scaturro,
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Eike Steinmann,
Roles Resources, Validation
Affiliation Department of Molecular and Medical Virology, Ruhr University Bochum, Bochum, Germany
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Ralf Bartenschlager,
Roles Formal analysis, Methodology, Resources, Validation, Writing – review & editing
Affiliations Heidelberg University, Medical Faculty Heidelberg, Department of Infectious Diseases, Molecular Virology, Center for Integrative Infectious Diseases Research, Heidelberg, Germany, German Center for Infection Research (DZIF), partner site Heidelberg, Heidelberg, Germany, German Cancer Research Center (DKFZ), Division Virus-Associated Carcinogenesis, Heidelberg, Germany
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Thomas Pietschmann,
Roles Funding acquisition, Project administration, Resources, Validation
Affiliations Institute for Experimental Virology, TWINCORE Centre for Experimental and Clinical Infection Research, a joint venture between the Helmholtz Centre for Infection Research and the Hannover Medical School, Hannover, Germany, Cluster of Excellence RESIST (EXC 2155), Hannover Medical School, Hannover, Germany
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Joerg Heeren,
Roles Methodology, Resources, Validation
Affiliation Department of Biochemistry and Molecular Cell Biology, Center for Experimental Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
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Chris Lauber,
Roles Formal analysis, Validation, Visualization, Writing – review & editing
Affiliations Institute for Experimental Virology, TWINCORE Centre for Experimental and Clinical Infection Research, a joint venture between the Helmholtz Centre for Infection Research and the Hannover Medical School, Hannover, Germany, Cluster of Excellence RESIST (EXC 2155), Hannover Medical School, Hannover, Germany
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Gabrielle Vieyres
Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing
* E-mail: gabrielle.vieyres@uni-luebeck.de
Affiliations Leibniz Institute of Virology (LIV), Hamburg, Germany, Integrative Analysis of Pathogen-Induced Compartments, Leibniz ScienceCampus InterACt, Hamburg, Germany, Institute of Virology and Cell Biology, University of Luebeck, Luebeck, Germany
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The triglyceride-synthesizing enzyme diacylglycerol acyltransferase 2 modulates the formation of the hepatitis C virus replication organelle
- Isabelle Reichert,
- Ji-Young Lee,
- Laura Weber,
- Marceline M. Fuh,
- Lina Schlaeger,
- Stefanie Rößler,
- Volker Kinast,
- Sarah Schlienkamp,
- Janina Conradi,
- Florian W. R. Vondran
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- Published: September 6, 2024
- https://doi.org/10.1371/journal.ppat.1012509