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Open Access
Peer-reviewed
Research Article
Rab27a GTPase and its effector Myosin Va are host factors required for efficient Oropouche virus cell egress
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Juan O. Concha ,
Contributed equally to this work with: Juan O. Concha, Kristel Gutierrez
Roles Conceptualization, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing
Affiliations Virus Research Center, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil, Department of Cell and Molecular Biology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil
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Kristel Gutierrez ,
Contributed equally to this work with: Juan O. Concha, Kristel Gutierrez
Roles Investigation, Methodology, Visualization, Writing – review & editing
Affiliations Virus Research Center, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil, Department of Cell and Molecular Biology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil
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Natalia Barbosa,
Roles Formal analysis, Investigation, Methodology, Visualization, Writing – review & editing
Affiliations Virus Research Center, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil, Department of Cell and Molecular Biology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil, Department of Pathology, University of Cambridge, Cambridge, United Kingdom
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Roger L. Rodrigues,
Roles Investigation, Methodology, Writing – review & editing
Affiliations Virus Research Center, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil, Department of Cell and Molecular Biology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil
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Andreia N. de Carvalho,
Roles Investigation, Methodology, Writing – review & editing
Affiliations Virus Research Center, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil, Department of Cell and Molecular Biology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil
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Lucas A. Tavares,
Roles Investigation, Methodology, Writing – review & editing
Affiliations Virus Research Center, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil, Department of Cell and Molecular Biology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil
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Jared S. Rudd,
Roles Investigation, Methodology, Writing – review & editing
Affiliations Virus Research Center, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil, Department of Cell and Molecular Biology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil
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Cristina S. Costa,
Roles Investigation, Writing – review & editing
Affiliations Virus Research Center, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil, Department of Cell and Molecular Biology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil
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Barbara Y. G. Andrade,
Roles Investigation, Writing – review & editing
Affiliation Department of Cell and Molecular Biology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil
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Enilza M. Espreafico,
Roles Conceptualization, Methodology, Supervision, Validation, Writing – review & editing
Affiliation Department of Cell and Molecular Biology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil
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Colin M. Crump,
Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Resources, Supervision, Validation, Visualization, Writing – review & editing
Affiliation Department of Pathology, University of Cambridge, Cambridge, United Kingdom
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Luis L. P. daSilva
Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Project administration, Resources, Supervision, Visualization, Writing – original draft, Writing – review & editing
* E-mail: lldasilva@fmrp.usp.br
Affiliations Virus Research Center, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil, Department of Cell and Molecular Biology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil
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Rab27a GTPase and its effector Myosin Va are host factors required for efficient Oropouche virus cell egress
- Juan O. Concha,
- Kristel Gutierrez,
- Natalia Barbosa,
- Roger L. Rodrigues,
- Andreia N. de Carvalho,
- Lucas A. Tavares,
- Jared S. Rudd,
- Cristina S. Costa,
- Barbara Y. G. Andrade,
- Enilza M. Espreafico
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- Published: August 30, 2024
- https://doi.org/10.1371/journal.ppat.1012504