Cell-intrinsic regulation of phagocyte function by interferon lambda during pulmonary viral, bacterial super-infection

Danielle Antos; Olivia B. Parks; Alexis M. Duray; Nevil Abraham; Joshua J. Michel; Saran Kupul; Rosemary Westcott; John F. Alcorn

doi:10.1371/journal.ppat.1012498

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Open Access

Peer-reviewed

Research Article

Cell-intrinsic regulation of phagocyte function by interferon lambda during pulmonary viral, bacterial super-infection

Danielle Antos,

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

Affiliations Department of Pediatrics, UPMC Children’s Hospital of Pittsburgh, Pittsburgh, Pennsylvania, United States of America, Department of Immunology, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
⨯
Olivia B. Parks,

Roles Investigation, Methodology

Affiliation Department of Pediatrics, UPMC Children’s Hospital of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
⨯
Alexis M. Duray,

Roles Investigation

Affiliations Department of Pediatrics, UPMC Children’s Hospital of Pittsburgh, Pittsburgh, Pennsylvania, United States of America, Department of Immunology, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
⨯
Nevil Abraham,

Roles Investigation, Methodology

Affiliation Department of Immunology, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
⨯
Joshua J. Michel,

Roles Investigation, Methodology

Affiliation Department of Pediatrics, UPMC Children’s Hospital of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
⨯
Saran Kupul,

Roles Investigation, Methodology

Affiliation Department of Pediatrics, UPMC Children’s Hospital of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
⨯
Rosemary Westcott,

Roles Investigation, Methodology

Affiliation Department of Pediatrics, UPMC Children’s Hospital of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
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John F. Alcorn

Roles Conceptualization, Formal analysis, Funding acquisition, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

* E-mail: john.alcorn@chp.edu

Affiliations Department of Pediatrics, UPMC Children’s Hospital of Pittsburgh, Pittsburgh, Pennsylvania, United States of America, Department of Immunology, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

https://orcid.org/0000-0001-5997-7711

⨯

Cell-intrinsic regulation of phagocyte function by interferon lambda during pulmonary viral, bacterial super-infection

Danielle Antos,
Olivia B. Parks,
Alexis M. Duray,
Nevil Abraham,
Joshua J. Michel,
Saran Kupul,
Rosemary Westcott,
John F. Alcorn

Published: August 23, 2024
https://doi.org/10.1371/journal.ppat.1012498

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