Dual-role epitope on SARS-CoV-2 spike enhances and neutralizes viral entry across different variants

• Gang Ye ,

  Contributed equally to this work with: Gang Ye, Fan Bu

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Validation, Writing – review & editing

  Affiliations Department of Pharmacology, University of Minnesota Medical School, Minneapolis, Minnesota, United States of America, Center for Emerging Viruses, University of Minnesota, Minneapolis, Minnesota, United States of America

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• Fan Bu ,

  Contributed equally to this work with: Gang Ye, Fan Bu

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Validation, Writing – review & editing

  Affiliations Department of Pharmacology, University of Minnesota Medical School, Minneapolis, Minnesota, United States of America, Center for Emerging Viruses, University of Minnesota, Minneapolis, Minnesota, United States of America

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• Ruangang Pan,

  Roles Data curation, Formal analysis, Investigation, Validation, Writing – review & editing

  Affiliation Department of Microbiology and Immunology, University of Iowa, Iowa City, Iowa, United States of America

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• Alise Mendoza,

  Roles Data curation, Formal analysis, Investigation, Validation, Writing – review & editing

  Affiliations Department of Pharmacology, University of Minnesota Medical School, Minneapolis, Minnesota, United States of America, Center for Emerging Viruses, University of Minnesota, Minneapolis, Minnesota, United States of America

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• Divyasha Saxena,

  Roles Data curation, Formal analysis, Investigation, Validation, Writing – review & editing

  Affiliation Center for Predictive Medicine, University of Louisville, Louisville, Kentucky, United States of America

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• Jian Zheng,

  Roles Formal analysis, Supervision, Validation, Writing – review & editing

  Affiliations Center for Predictive Medicine, University of Louisville, Louisville, Kentucky, United States of America, Department of Microbiology and Immunology, University of Louisville, Louisville, Kentucky, United States of America

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• Stanley Perlman,

  Roles Formal analysis, Supervision, Validation, Writing – review & editing

  Affiliation Department of Microbiology and Immunology, University of Iowa, Iowa City, Iowa, United States of America

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• Bin Liu ,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Supervision, Validation, Writing – review & editing

  * E-mail: liu00794@umn.edu (BL); lifang@umn.edu (FL)

  Affiliation Hormel Institute, University of Minnesota, Austin, Minnesota, United States of America

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• Fang Li

  Roles Conceptualization, Formal analysis, Funding acquisition, Project administration, Supervision, Validation, Writing – original draft

  * E-mail: liu00794@umn.edu (BL); lifang@umn.edu (FL)

  Affiliations Department of Pharmacology, University of Minnesota Medical School, Minneapolis, Minnesota, United States of America, Center for Emerging Viruses, University of Minnesota, Minneapolis, Minnesota, United States of America

  https://orcid.org/0000-0002-1958-366X

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