Changes in cerebrospinal fluid proteins across the spectrum of untreated and treated chronic HIV-1 infection

• Zicheng Hu,

  Roles Data curation, Formal analysis, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Bakar Computational Health Sciences Institute, University of California San Francisco, San Francisco, California, United States of America

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• Paola Cinque,

  Roles Investigation, Resources, Writing – review & editing

  Affiliations Unit of Neurovirology, San Raffaele Hospital, Milan, Italy, Unit of Infectious Diseases, San Raffaele Hospital, Milan, Italy

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• Ameet Dravid,

  Roles Investigation, Resources, Writing – review & editing

  Affiliations HIV Medicine and Infectious Diseases, Poona Hospital and Research Centre, Pune, India, Noble Hospital and Research Centre, Pune, India, Ruby Hall Clinic, Pune, India

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• Lars Hagberg,

  Roles Investigation, Resources, Writing – review & editing

  Affiliations Department of Infectious Diseases, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden, Region Västra Götaland, Sahlgrenska University Hospital, Department of Infectious Diseases, Gothenburg, Sweden

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• Aylin Yilmaz,

  Roles Investigation, Resources, Writing – review & editing

  Affiliations Department of Infectious Diseases, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden, Region Västra Götaland, Sahlgrenska University Hospital, Department of Infectious Diseases, Gothenburg, Sweden

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• Henrik Zetterberg,

  Roles Investigation, Writing – review & editing

  Affiliations Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry, the Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden, Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden, Department of Neurodegenerative Disease, UCL Institute of Neurology, London, United Kingdom, UK Dementia Research Institute at UCL, London, United Kingdom, Hong Kong Center for Neurodegenerative Diseases, Clear Water Bay, Hong Kong, China, Wisconsin Alzheimer’s Disease Research Center, University of Wisconsin School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin, United States of America

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• Dietmar Fuchs,

  Roles Investigation, Writing – review & editing

  Affiliation Institute of Medical Biological Chemistry, Innsbruck Medical University, Innsbruck, Austria

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• Johanna Gostner,

  Roles Investigation, Writing – review & editing

  Affiliation Institute of Medical Biological Chemistry, Innsbruck Medical University, Innsbruck, Austria

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• Kaj Blennow,

  Roles Writing – review & editing

  Affiliations Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry, the Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden, Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden

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• Serena S. Spudich,

  Roles Investigation, Writing – review & editing

  Affiliation Department of Neurology, Yale University School of Medicine, New Haven, Connecticut, United States of America

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• Laura Kincer,

  Roles Writing – review & editing

  Affiliations Department of Microbiology and Immunology, University of North Carolina, Chapel Hill, North Carolina, United States of America, Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, North Carolina, United States of America

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• Shuntai Zhou,

  Roles Data curation, Formal analysis

  Affiliations Department of Microbiology and Immunology, University of North Carolina, Chapel Hill, North Carolina, United States of America, Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, North Carolina, United States of America

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• Sarah Beth Joseph,

  Roles Writing – review & editing

  Affiliations Department of Microbiology and Immunology, University of North Carolina, Chapel Hill, North Carolina, United States of America, Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, North Carolina, United States of America, UNC HIV Cure Center, University of North Carolina, Chapel Hill, North Carolina, United States of America

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• Ronald Swanstrom,

  Roles Supervision, Writing – review & editing

  Affiliations Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, North Carolina, United States of America, UNC Center for AIDS Research, University of North Carolina, Chapel Hill, North Carolina, United States of America, Department of Biochemistry and Biophysics, University of North Carolina, Chapel Hill, North Carolina, United States of America

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• Richard W. Price ,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Resources, Supervision, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: richard.price@ucsf.edu

  ¶‡ These authors are joint senior authors on this work.

  Affiliation Department of Neurology, University of California San Francisco, San Francisco, California, United States of America

  https://orcid.org/0000-0001-5429-6044

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•  [ ... ],
• Magnus Gisslén

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Resources, Supervision, Visualization, Writing – original draft, Writing – review & editing

  ¶‡ These authors are joint senior authors on this work.

  Affiliations Department of Infectious Diseases, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden, Region Västra Götaland, Sahlgrenska University Hospital, Department of Infectious Diseases, Gothenburg, Sweden, Public Health Agency of Sweden, Solna, Sweden

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