Characterization of Entamoeba fatty acid elongases; validation as targets and provision of promising leads for new drugs against amebiasis

• Fumika Mi-ichi ,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Project administration, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: fumika@nagasaki-u.ac.jp

  Affiliations Central Laboratory, Institute of Tropical Medicine (NEKKEN), Nagasaki University, Nagasaki, Japan, Division of Molecular and Cellular Immunoscience, Department of Biomolecular Sciences, Faculty of Medicine, Saga University, Saga, Japan

  https://orcid.org/0000-0001-7042-2266

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• Hiroshi Tsugawa,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Department of Biotechnology and Life Science, Tokyo University of Agriculture and Technology, Tokyo, Japan, Laboratory for Metabolomics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan, Graduate School of Medical Life Science, Yokohama City University, Yokohama, Japan

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• Tam Kha Vo,

  Roles Formal analysis, Investigation, Validation, Visualization

  Affiliations Central Laboratory, Institute of Tropical Medicine (NEKKEN), Nagasaki University, Nagasaki, Japan, Division of Molecular and Cellular Immunoscience, Department of Biomolecular Sciences, Faculty of Medicine, Saga University, Saga, Japan

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• Yuto Kurizaki,

  Roles Formal analysis, Investigation, Methodology, Validation

  Affiliation Department of Biotechnology and Life Science, Tokyo University of Agriculture and Technology, Tokyo, Japan

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• Hiroki Yoshida,

  Roles Funding acquisition, Investigation, Validation, Writing – review & editing

  Affiliation Division of Molecular and Cellular Immunoscience, Department of Biomolecular Sciences, Faculty of Medicine, Saga University, Saga, Japan

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• Makoto Arita

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Validation, Writing – review & editing

  Affiliations Laboratory for Metabolomics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan, Graduate School of Medical Life Science, Yokohama City University, Yokohama, Japan, Division of Physiological Chemistry and Metabolism, Graduate School of Pharmaceutical Sciences, Keio University, Tokyo, Japan, Human Biology-Microbiome-Quantum Research Center (WPI-Bio2Q), Keio University, Tokyo, Japan

  https://orcid.org/0000-0001-9902-0463

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