Enolase inhibitors as therapeutic leads for Naegleria fowleri infection

• Jillian E. Milanes ,

  Roles Conceptualization, Investigation, Methodology, Supervision, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: jmilane@clemson.edu

  Affiliation Department of Genetics and Biochemistry, Eukaryotic Pathogens Innovation Center, Clemson University, Clemson, South Carolina, United States of America

  https://orcid.org/0000-0002-4872-082X

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• Victoria C. Yan,

  Roles Investigation, Methodology

  Affiliation Department of Cancer Systems Imaging, UT MD Anderson Cancer Center, Houston, Texas, United States of America

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• Cong-Dat Pham,

  Roles Investigation, Methodology

  Affiliation Department of Cancer Systems Imaging, UT MD Anderson Cancer Center, Houston, Texas, United States of America

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• Florian Muller,

  Roles Conceptualization, Methodology, Supervision, Writing – review & editing

  Affiliation Sporos Bioventures, Houston, Texas, United States of America

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• Samuel Kwain,

  Roles Investigation, Methodology, Visualization, Writing – original draft

  Affiliation Department of Chemistry, Eukaryotic Pathogens Innovation Center, Clemson University, Clemson, South Carolina, United States of America

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• Kerrick C. Rees,

  Roles Investigation, Methodology

  Affiliation Department of Chemistry, Eukaryotic Pathogens Innovation Center, Clemson University, Clemson, South Carolina, United States of America

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• Brian N. Dominy,

  Roles Conceptualization, Methodology, Supervision, Visualization, Writing – review & editing

  Affiliation Department of Chemistry, Eukaryotic Pathogens Innovation Center, Clemson University, Clemson, South Carolina, United States of America

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• Daniel C. Whitehead,

  Roles Conceptualization, Funding acquisition, Methodology, Supervision, Writing – original draft, Writing – review & editing

  Affiliation Department of Chemistry, Eukaryotic Pathogens Innovation Center, Clemson University, Clemson, South Carolina, United States of America

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• Steven W. Millward,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Department of Cancer Systems Imaging, UT MD Anderson Cancer Center, Houston, Texas, United States of America

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• Madison Bolejack,

  Roles Investigation, Methodology, Visualization

  Affiliation UCB BioSciences, Bainbridge Island, Washington, United States of America

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• Roger Shek,

  Roles Investigation, Methodology

  Affiliation Center for Emerging and Re-emerging Infectious Diseases and Seattle Structural Genomics Center for Infectious Disease, Center for Global Infection Disease Research, Seattle Children’s Research Institute, Seattle, Washington, United States of America

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• Logan Tillery,

  Roles Investigation, Methodology

  Affiliation Center for Emerging and Re-emerging Infectious Diseases and Seattle Structural Genomics Center for Infectious Disease, Center for Global Infection Disease Research, Seattle Children’s Research Institute, Seattle, Washington, United States of America

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• Isabelle Q. Phan,

  Roles Conceptualization, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Seattle Structural Genomics Center for Infectious Disease, Center for Global Infection Disease Research, Seattle Children’s Research Institute, Seattle, Washington, United States of America

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• Bart Staker,

  Roles Conceptualization, Investigation, Methodology, Writing – original draft

  Affiliation Seattle Structural Genomics Center for Infectious Disease, Center for Global Infection Disease Research, Seattle Children’s Research Institute, Seattle, Washington, United States of America

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• E. Ashley Moseman,

  Roles Conceptualization, Methodology, Writing – original draft

  Affiliation Department of Immunology, Duke University School of Medicine, Durham, North Carolina, United States of America

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• Xiang Zhang,

  Roles Investigation, Methodology, Visualization, Writing – original draft

  Affiliation Department of Chemistry, University of Louisville, Louisville, Kentucky, United States of America

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• Xipeng Ma,

  Roles Investigation, Methodology, Visualization, Writing – original draft

  Affiliation Department of Chemistry, University of Louisville, Louisville, Kentucky, United States of America

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• Audriy Jebet,

  Roles Investigation, Methodology, Visualization, Writing – original draft

  Affiliation Department of Chemistry, University of Louisville, Louisville, Kentucky, United States of America

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• Xinmin Yin,

  Roles Investigation, Methodology, Supervision, Visualization, Writing – original draft

  Affiliation Department of Chemistry, University of Louisville, Louisville, Kentucky, United States of America

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•  [ ... ],
• James C. Morris

  Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – original draft, Writing – review & editing

  Affiliation Department of Genetics and Biochemistry, Eukaryotic Pathogens Innovation Center, Clemson University, Clemson, South Carolina, United States of America

  https://orcid.org/0000-0003-2515-5714

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