The assembly of neutrophil inflammasomes during COVID-19 is mediated by type I interferons

• Luz E. Cabrera ,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Software, Validation, Visualization, Writing – original draft

  * E-mail: luz.cabreralara@helsinki.fi

  Affiliation Viral Zoonosis Research Unit, Medicum, Department of Virology, University of Helsinki, Helsinki, Finland

  https://orcid.org/0000-0001-9437-1010

  ⨯
• Suvi T. Jokiranta,

  Roles Investigation, Writing – review & editing

  Affiliations Department of Bacteriology and Immunology, University of Helsinki, Helsinki, Finland, Translational Immunology Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland

  ⨯
• Sanna Mäki,

  Roles Investigation

  Affiliation Viral Zoonosis Research Unit, Medicum, Department of Virology, University of Helsinki, Helsinki, Finland

  ⨯
• Simo Miettinen,

  Roles Investigation

  Affiliations Viral Zoonosis Research Unit, Medicum, Department of Virology, University of Helsinki, Helsinki, Finland, Department of Veterinary Biosciences, University of Helsinki, Helsinki, Finland

  ⨯
• Ravi Kant,

  Roles Resources

  Affiliations Viral Zoonosis Research Unit, Medicum, Department of Virology, University of Helsinki, Helsinki, Finland, Department of Veterinary Biosciences, University of Helsinki, Helsinki, Finland, Department of Tropical Parasitology, Institute of Maritime and Tropical Medicine, Medical University of Gdansk, Gdynia, Poland

  ⨯
• Lauri Kareinen,

  Roles Investigation, Writing – review & editing

  Affiliations Viral Zoonosis Research Unit, Medicum, Department of Virology, University of Helsinki, Helsinki, Finland, Department of Veterinary Biosciences, University of Helsinki, Helsinki, Finland

  ⨯
• Tarja Sironen,

  Roles Resources

  Affiliations Viral Zoonosis Research Unit, Medicum, Department of Virology, University of Helsinki, Helsinki, Finland, Department of Veterinary Biosciences, University of Helsinki, Helsinki, Finland

  ⨯
• Jukka-Pekka Pietilä,

  Roles Resources

  Affiliations Human Microbiome Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland, Meilahti Vaccine Research Center MeVac, Department of Infectious Diseases, Inflammation Center, Helsinki University Hospital and University of Helsinki, Helsinki, Finland

  ⨯
• Anu Kantele,

  Roles Funding acquisition, Resources, Writing – review & editing

  Affiliations Human Microbiome Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland, Meilahti Vaccine Research Center MeVac, Department of Infectious Diseases, Inflammation Center, Helsinki University Hospital and University of Helsinki, Helsinki, Finland

  ⨯
• Eliisa Kekäläinen,

  Roles Supervision, Writing – review & editing

  Affiliations Department of Bacteriology and Immunology, University of Helsinki, Helsinki, Finland, Translational Immunology Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland, Division of Virology and Immunology, HUSLAB Clinical Microbiology, HUS Diagnostic Center, Helsinki University Hospital, Helsinki, Finland

  ⨯
• Hanna Lindgren,

  Roles Resources

  Affiliation Institute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki, Helsinki, Finland

  ⨯
• Pirkko Mattila,

  Roles Resources, Writing – review & editing

  Affiliation Institute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki, Helsinki, Finland

  ⨯
• Anja Kipar,

  Roles Investigation, Methodology, Supervision, Validation, Visualization, Writing – review & editing

  Affiliations Department of Veterinary Biosciences, University of Helsinki, Helsinki, Finland, Laboratory for Animal Model Pathology, Institute of Veterinary Pathology, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland, Department of Infection Biology & Microbiomes, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, United Kingdom

  ⨯
• Olli Vapalahti,

  Roles Funding acquisition, Resources

  Affiliations Viral Zoonosis Research Unit, Medicum, Department of Virology, University of Helsinki, Helsinki, Finland, Department of Veterinary Biosciences, University of Helsinki, Helsinki, Finland, Division of Virology and Immunology, HUSLAB Clinical Microbiology, HUS Diagnostic Center, Helsinki University Hospital, Helsinki, Finland

  ⨯
• Tomas Strandin

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Validation, Writing – original draft

  Affiliation Viral Zoonosis Research Unit, Medicum, Department of Virology, University of Helsinki, Helsinki, Finland

  ⨯