Activation loop phosphorylation and cGMP saturation of PKG regulate egress of malaria parasites

• Konstantinos Koussis ,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: konstantinos.kousis@lshtm.ac.uk (KK); mike.blackman@crick.ac.uk (MJB)

  Current address: Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, United Kingdom

  Affiliation Malaria Biochemistry Laboratory, Francis Crick Institute, London, United Kingdom

  https://orcid.org/0000-0002-6737-8724

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• Silvia Haase,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Host-Pathogen Interactions in Cryptosporidiosis Laboratory, The Francis Crick Institute, London, United Kingdom

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• Chrislaine Withers-Martinez,

  Roles Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – review & editing

  Affiliation Malaria Biochemistry Laboratory, Francis Crick Institute, London, United Kingdom

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• Helen R. Flynn,

  Roles Data curation, Formal analysis, Validation, Visualization, Writing – review & editing

  Affiliation Proteomics Science Technology Platform, The Francis Crick Institute, London, United Kingdom

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• Simone Kunzelmann,

  Roles Data curation, Formal analysis, Supervision, Writing – review & editing

  Affiliation Structural Biology Science Technology Platform, The Francis Crick Institute, London, United Kingdom

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• Evangelos Christodoulou,

  Roles Data curation, Formal analysis, Validation, Writing – review & editing

  Affiliation Structural Biology Science Technology Platform, The Francis Crick Institute, London, United Kingdom

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• Fairouz Ibrahim,

  Roles Data curation, Formal analysis, Validation, Visualization, Writing – review & editing

  Affiliation Proteomics Science Technology Platform, The Francis Crick Institute, London, United Kingdom

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• Mark Skehel,

  Roles Formal analysis, Methodology, Supervision, Writing – review & editing

  Affiliation Proteomics Science Technology Platform, The Francis Crick Institute, London, United Kingdom

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• David A. Baker,

  Roles Conceptualization, Funding acquisition, Supervision, Writing – original draft, Writing – review & editing

  Affiliation Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, United Kingdom

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• Michael J. Blackman

  Roles Conceptualization, Funding acquisition, Investigation, Supervision, Validation, Writing – original draft, Writing – review & editing

  * E-mail: konstantinos.kousis@lshtm.ac.uk (KK); mike.blackman@crick.ac.uk (MJB)

  Affiliations Malaria Biochemistry Laboratory, Francis Crick Institute, London, United Kingdom, Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, United Kingdom

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