The NS2B-PP1α-eIF2α axis: Inhibiting stress granule formation and Boosting Zika virus replication

• Xiaoyan Wu ,

  Contributed equally to this work with: Xiaoyan Wu, Linliang Zhang

  Roles Conceptualization, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation State Key Laboratory of Virology and Modern Virology Research Center, College of Life Sciences, Wuhan University, Wuhan, China

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• Linliang Zhang ,

  Contributed equally to this work with: Xiaoyan Wu, Linliang Zhang

  Roles Investigation, Methodology, Validation, Visualization, Writing – original draft

  Affiliation College of Life Sciences, Hubei University, Wuhan, China

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• Cong Liu,

  Roles Investigation, Resources

  Affiliation State Key Laboratory of Virology and Modern Virology Research Center, College of Life Sciences, Wuhan University, Wuhan, China

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• Qi Cheng,

  Roles Resources

  Affiliation Wuhan Jinyintan Hospital, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, China

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• Wen Zhao,

  Roles Methodology, Resources

  Affiliation Tissue Engineering and Organ Manufacturing (TEOM) lab, Department of Biomedical Engineering, Wuhan University Taikang Medical School (School of Basic Medical Sciences), Wuhan, China

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• Pu Chen,

  Roles Methodology, Resources

  Affiliations Tissue Engineering and Organ Manufacturing (TEOM) lab, Department of Biomedical Engineering, Wuhan University Taikang Medical School (School of Basic Medical Sciences), Wuhan, China, Taikang Center for Life and Medical Sciences, Wuhan University, Wuhan, China

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• Yali Qin ,

  Roles Formal analysis, Funding acquisition, Methodology, Project administration, Validation, Writing – original draft

  * E-mail: yqin@whu.edu.cn (YQ); chenmz@whu.edu.cn (MC)

  Affiliations State Key Laboratory of Virology and Modern Virology Research Center, College of Life Sciences, Wuhan University, Wuhan, China, College of Life Sciences, Hubei University, Wuhan, China

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• Mingzhou Chen

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: yqin@whu.edu.cn (YQ); chenmz@whu.edu.cn (MC)

  Affiliations State Key Laboratory of Virology and Modern Virology Research Center, College of Life Sciences, Wuhan University, Wuhan, China, College of Life Sciences, Hubei University, Wuhan, China, Taikang Center for Life and Medical Sciences, Wuhan University, Wuhan, China, Hubei Jiangxia Laboratory, Wuhan, China

  https://orcid.org/0000-0001-5308-6897

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