Norwegian moose CWD induces clinical disease and neuroinvasion in gene-targeted mice expressing cervid S138N prion protein

• Maria Immaculata Arifin ,

  Contributed equally to this work with: Maria Immaculata Arifin, Samia Hannaoui

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Faculty of Veterinary Medicine, University of Calgary, Calgary, Canada

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• Samia Hannaoui ,

  Contributed equally to this work with: Maria Immaculata Arifin, Samia Hannaoui

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Supervision, Validation, Visualization, Writing – review & editing

  Affiliation Faculty of Veterinary Medicine, University of Calgary, Calgary, Canada

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• Raychal Ashlyn Ng,

  Roles Data curation, Investigation, Methodology, Writing – review & editing

  Affiliation Faculty of Veterinary Medicine, University of Calgary, Calgary, Canada

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• Doris Zeng,

  Roles Data curation, Investigation, Methodology, Writing – review & editing

  Affiliation Faculty of Veterinary Medicine, University of Calgary, Calgary, Canada

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• Irina Zemlyankina,

  Roles Data curation, Investigation, Methodology, Writing – review & editing

  Affiliation Faculty of Veterinary Medicine, University of Calgary, Calgary, Canada

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• Hanaa Ahmed-Hassan,

  Roles Data curation, Investigation, Methodology, Writing – review & editing

  Affiliations Faculty of Veterinary Medicine, University of Calgary, Calgary, Canada, Zoonoses Department, Faculty of Veterinary Medicine, Cairo University, Giza, Egypt

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• Hermann M. Schatzl,

  Roles Funding acquisition, Writing – review & editing

  Affiliations Faculty of Veterinary Medicine, University of Calgary, Calgary, Canada, Hotchkiss Brain Institute, University of Calgary, Calgary, Canada, Snyder Institute for Chronic Diseases, University of Calgary, Calgary, Canada

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• Lech Kaczmarczyk,

  Roles Methodology, Resources, Writing – review & editing

  Affiliation Linköping University, Linköping, Sweden

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• Walker S. Jackson,

  Roles Methodology, Resources, Writing – review & editing

  Affiliation Linköping University, Linköping, Sweden

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• Sylvie L. Benestad,

  Roles Conceptualization, Resources, Writing – review & editing

  Affiliation Norwegian Veterinary Institute, Ås, Norway

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• Sabine Gilch

  Roles Conceptualization, Funding acquisition, Project administration, Resources, Supervision, Validation, Writing – original draft, Writing – review & editing

  * E-mail: sgilch@ucalgary.ca

  Affiliations Faculty of Veterinary Medicine, University of Calgary, Calgary, Canada, Hotchkiss Brain Institute, University of Calgary, Calgary, Canada, Snyder Institute for Chronic Diseases, University of Calgary, Calgary, Canada

  https://orcid.org/0000-0001-5923-3464

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