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Open Access
Peer-reviewed
Research Article
Harvesting and amplifying gene cassettes confers cross-resistance to critically important antibiotics
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Punyawee Dulyayangkul,
Roles Formal analysis, Investigation, Writing – original draft, Writing – review & editing
Affiliations School of Cellular & Molecular Medicine, University of Bristol, Bristol, United Kingdom, Laboratory of Biotechnology, Chulabhorn Research Institute, Bangkok, Thailand
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Thomas Beavis,
Roles Formal analysis, Investigation, Writing – original draft, Writing – review & editing
Current Address: European Molecular Biology Laboratory, Heidelberg, Germany
Affiliation School of Cellular & Molecular Medicine, University of Bristol, Bristol, United Kingdom
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Winnie W. Y. Lee,
Roles Formal analysis, Investigation, Writing – review & editing
Affiliation School of Cellular & Molecular Medicine, University of Bristol, Bristol, United Kingdom
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Robbie Ardagh,
Roles Formal analysis, Investigation, Writing – review & editing
Affiliation School of Cellular & Molecular Medicine, University of Bristol, Bristol, United Kingdom
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Frances Edwards,
Roles Conceptualization, Formal analysis, Investigation, Writing – review & editing
Affiliations School of Cellular & Molecular Medicine, University of Bristol, Bristol, United Kingdom, North Bristol NHS Trust, Bristol, United Kingdom
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Fergus Hamilton,
Roles Conceptualization, Writing – review & editing
Affiliation North Bristol NHS Trust, Bristol, United Kingdom
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Ian Head,
Roles Formal analysis, Investigation, Writing – review & editing
Affiliations School of Cellular & Molecular Medicine, University of Bristol, Bristol, United Kingdom, Somerset NHS Foundation Trust, Taunton, United Kingdom
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Kate J. Heesom,
Roles Formal analysis, Funding acquisition, Investigation, Writing – review & editing
Affiliation Bristol University Proteomics Facility, University of Bristol, Bristol, United Kingdom
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Oliver Mounsey,
Roles Investigation, Supervision, Writing – review & editing
Affiliation School of Cellular & Molecular Medicine, University of Bristol, Bristol, United Kingdom
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Marek Murarik,
Roles Formal analysis, Investigation, Writing – review & editing
Affiliation School of Cellular & Molecular Medicine, University of Bristol, Bristol, United Kingdom
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Peechanika Pinweha,
Roles Formal analysis, Investigation, Writing – review & editing
Affiliation School of Cellular & Molecular Medicine, University of Bristol, Bristol, United Kingdom
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Carlos Reding,
Roles Formal analysis, Methodology, Software, Writing – review & editing
Affiliation School of Cellular & Molecular Medicine, University of Bristol, Bristol, United Kingdom
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Naphat Satapoomin,
Roles Formal analysis, Investigation, Writing – review & editing
Affiliation School of Cellular & Molecular Medicine, University of Bristol, Bristol, United Kingdom
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John M. Shaw,
Roles Formal analysis, Investigation, Writing – review & editing
Affiliation School of Cellular & Molecular Medicine, University of Bristol, Bristol, United Kingdom
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Yuiko Takebayashi,
Roles Formal analysis, Investigation, Writing – review & editing
Affiliation School of Cellular & Molecular Medicine, University of Bristol, Bristol, United Kingdom
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Catherine L. Tooke,
Roles Investigation, Supervision, Writing – review & editing
Affiliation School of Cellular & Molecular Medicine, University of Bristol, Bristol, United Kingdom
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James Spencer,
Roles Conceptualization, Supervision, Writing – review & editing
Affiliation School of Cellular & Molecular Medicine, University of Bristol, Bristol, United Kingdom
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Philip B. Williams,
Roles Conceptualization, Formal analysis, Funding acquisition, Supervision, Writing – review & editing
Affiliations School of Cellular & Molecular Medicine, University of Bristol, Bristol, United Kingdom, University Hospitals Bristol and Weston NHS Foundation Trust, Bristol, United Kingdom
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Matthew B. Avison
Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Supervision, Visualization, Writing – original draft, Writing – review & editing
* E-mail: bimba@bristol.ac.uk
Affiliation School of Cellular & Molecular Medicine, University of Bristol, Bristol, United Kingdom
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Harvesting and amplifying gene cassettes confers cross-resistance to critically important antibiotics
- Punyawee Dulyayangkul,
- Thomas Beavis,
- Winnie W. Y. Lee,
- Robbie Ardagh,
- Frances Edwards,
- Fergus Hamilton,
- Ian Head,
- Kate J. Heesom,
- Oliver Mounsey,
- Marek Murarik
- Published: June 6, 2024
- https://doi.org/10.1371/journal.ppat.1012235