Quinoxaline-based anti-schistosomal compounds have potent anti-plasmodial activity

• Mukul Rawat,

  Roles Conceptualization, Investigation, Writing – original draft, Writing – review & editing

  Affiliations Biological Chemistry and Drug Discovery, Wellcome Centre for Anti-Infectives Research, University of Dundee, Dundee, United Kingdom, Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, United Kingdom

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• Gilda Padalino,

  Roles Conceptualization, Writing – original draft, Writing – review & editing

  Affiliations Department of Life Sciences (DLS), Aberystwyth University, Aberystwyth, United Kingdom, Swansea University Medical School, Swansea, United Kingdom

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• Edem Adika,

  Roles Investigation, Writing – review & editing

  Affiliation Biological Chemistry and Drug Discovery, Wellcome Centre for Anti-Infectives Research, University of Dundee, Dundee, United Kingdom

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• John Okombo,

  Roles Investigation, Writing – review & editing

  Affiliations Department of Microbiology and Immunology, Columbia University Irving Medical Center, New York, New York, United States of America, Center for Malaria Therapeutics and Antimicrobial Resistance, Division of Infectious Diseases, Department of Medicine, Columbia University Irving Medical Center, New York, New York, United States of America

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• Tomas Yeo,

  Roles Formal analysis, Investigation, Writing – review & editing

  Affiliations Department of Microbiology and Immunology, Columbia University Irving Medical Center, New York, New York, United States of America, Center for Malaria Therapeutics and Antimicrobial Resistance, Division of Infectious Diseases, Department of Medicine, Columbia University Irving Medical Center, New York, New York, United States of America

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• Andrea Brancale,

  Roles Supervision, Writing – review & editing

  Affiliation Department of Organic Chemistry, University of Chemistry and Technology Prague, Prague, Czech Republic

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• David A. Fidock,

  Roles Funding acquisition, Resources, Supervision, Writing – original draft, Writing – review & editing

  Affiliations Department of Microbiology and Immunology, Columbia University Irving Medical Center, New York, New York, United States of America, Center for Malaria Therapeutics and Antimicrobial Resistance, Division of Infectious Diseases, Department of Medicine, Columbia University Irving Medical Center, New York, New York, United States of America

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• Karl F. Hoffmann,

  Roles Conceptualization, Funding acquisition, Resources, Supervision, Writing – original draft, Writing – review & editing

  Affiliation Department of Life Sciences (DLS), Aberystwyth University, Aberystwyth, United Kingdom

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• Marcus C. S. Lee

  Roles Conceptualization, Funding acquisition, Investigation, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: mlee001@dundee.ac.uk

  Affiliations Biological Chemistry and Drug Discovery, Wellcome Centre for Anti-Infectives Research, University of Dundee, Dundee, United Kingdom, Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, United Kingdom

  https://orcid.org/0000-0002-4973-0915

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