Beyond the VSG layer: Exploring the role of intrinsic disorder in the invariant surface glycoproteins of African trypanosomes

• Hagen Sülzen,

  Roles Formal analysis, Investigation, Visualization, Writing – original draft

  Affiliations Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Prague, Czech Republic, Faculty of Science, Charles University, Prague, Czech Republic

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• Alexander N. Volkov,

  Roles Formal analysis, Methodology

  Affiliations VIB-VUB Center for Structural Biology, Flemish Institute of Biotechnology (VIB), Brussels, Belgium, Jean Jeener NMR Centre, Vrije Universiteit Brussel (VUB), Brussels, Belgium

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• Rob Geens,

  Roles Investigation

  Affiliations VIB-VUB Center for Structural Biology, Flemish Institute of Biotechnology (VIB), Brussels, Belgium, Laboratory of Medical Biochemistry (LMB) and the Infla-Med Center of Excellence, Department of Pharmaceutical Sciences, Universiteit of Antwerp, Wilrijk, Belgium

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• Farnaz Zahedifard,

  Roles Investigation

  Affiliation Department of Parasitology, Faculty of Science, Charles University in Prague, Biocev, Vestec, Czech Republic

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• Benoit Stijlemans,

  Roles Investigation, Methodology

  Affiliations Brussels Center for Immunology (BCIM), Department of Bioengineering Sciences, Vrije Universiteit Brussel, Brussels, Belgium, Myeloid Cell Immunology Laboratory, VIB Center for Inflammation Research, Brussels, Belgium

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• Martin Zoltner,

  Roles Investigation, Supervision

  Affiliation Department of Parasitology, Faculty of Science, Charles University in Prague, Biocev, Vestec, Czech Republic

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• Stefan Magez,

  Roles Investigation, Methodology

  Affiliations Brussels Center for Immunology (BCIM), Department of Bioengineering Sciences, Vrije Universiteit Brussel, Brussels, Belgium, Department of Biochemistry and Microbiology, Ghent University, Gent, Belgium, Laboratory for Biomedical Research, Department of Molecular Biotechnology, Environment Technology and Food Technology, Ghent University Global Campus, Incheon, South Korea

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• Yann G.-J. Sterckx ,

  Contributed equally to this work with: Yann G.-J. Sterckx, Sebastian Zoll

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: yann.sterckx@uantwerpen.be (YG-JS); sebastian.zoll@uochb.cas.cz (SZ)

  ¶‡ These authors are joint senior authors on this work.

  Affiliation Laboratory of Medical Biochemistry (LMB) and the Infla-Med Center of Excellence, Department of Pharmaceutical Sciences, Universiteit of Antwerp, Wilrijk, Belgium

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• Sebastian Zoll

  Contributed equally to this work with: Yann G.-J. Sterckx, Sebastian Zoll

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: yann.sterckx@uantwerpen.be (YG-JS); sebastian.zoll@uochb.cas.cz (SZ)

  ¶‡ These authors are joint senior authors on this work.

  Affiliation Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Prague, Czech Republic

  https://orcid.org/0000-0001-5376-9698

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