Design and characterization of protective pan-ebolavirus and pan-filovirus bispecific antibodies

• Ariel S. Wirchnianski ,

  Contributed equally to this work with: Ariel S. Wirchnianski, Elisabeth K. Nyakatura, Andrew S. Herbert

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Resources, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York, United States of America, Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, New York, United States of America

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• Elisabeth K. Nyakatura ,

  Contributed equally to this work with: Ariel S. Wirchnianski, Elisabeth K. Nyakatura, Andrew S. Herbert

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Resources, Validation, Visualization, Writing – original draft, Writing – review & editing

  Current address: Sanders Tri-Institutional Therapeutics Discovery Institute, Rockefeller University, New York, New York, United States of America

  Affiliation Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York, United States of America

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• Andrew S. Herbert ,

  Contributed equally to this work with: Ariel S. Wirchnianski, Elisabeth K. Nyakatura, Andrew S. Herbert

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: andrew.s.herbert4.civ@health.mil (ASH); kartik.chandran@einsteinmed.edu (KC); jon.lai@einsteinmed.edu (JRL)

  Affiliations Virology Division, United States Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America, The Geneva Foundation, Tacoma, Washington, United States of America

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• Ana I. Kuehne,

  Roles Data curation, Formal analysis, Investigation, Methodology, Resources, Validation, Visualization, Writing – review & editing

  Affiliation Virology Division, United States Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America

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• Shawn A. Abbasi,

  Roles Data curation, Formal analysis, Investigation, Methodology, Resources, Validation, Visualization, Writing – review & editing

  Affiliations Virology Division, United States Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America, The Geneva Foundation, Tacoma, Washington, United States of America

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• Catalina Florez,

  Roles Data curation, Formal analysis, Investigation, Methodology, Resources, Validation, Visualization, Writing – review & editing

  Affiliations Virology Division, United States Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America, The Geneva Foundation, Tacoma, Washington, United States of America

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• Nadia Storm,

  Roles Data curation, Formal analysis, Investigation, Methodology, Resources, Validation, Visualization, Writing – review & editing

  Affiliation Department of Virology, Immunology, and Microbiology; and National Emerging Infectious Diseases Laboratories, Boston University School of Medicine, Boston, Massachusetts, United States of America

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• Lindsay G. A. McKay,

  Roles Data curation, Formal analysis, Investigation, Methodology, Resources, Validation, Visualization, Writing – review & editing

  Affiliation Department of Virology, Immunology, and Microbiology; and National Emerging Infectious Diseases Laboratories, Boston University School of Medicine, Boston, Massachusetts, United States of America

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• Leandrew Dailey,

  Roles Data curation, Formal analysis, Investigation, Methodology, Resources, Validation, Visualization, Writing – review & editing

  Affiliation Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York, United States of America

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• Erin Kuang,

  Roles Data curation, Formal analysis, Investigation, Methodology, Resources, Validation, Visualization, Writing – review & editing

  Affiliation Mapp Biopharmaceutical Inc., San Diego, California, United States of America

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• Dafna M. Abelson,

  Roles Data curation, Formal analysis, Investigation, Methodology, Resources, Validation, Visualization, Writing – review & editing

  Affiliation Mapp Biopharmaceutical Inc., San Diego, California, United States of America

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• Anna Z. Wec,

  Roles Data curation, Formal analysis, Investigation, Methodology, Resources, Validation, Visualization, Writing – review & editing

  Current address: Department of Immunology, Infectious Disease Research, Moderna Therapeutics, Boston, Massachusetts, United States of America

  Affiliation Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, New York, United States of America

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• Srinjoy Chakraborti,

  Roles Data curation, Formal analysis, Investigation, Methodology, Resources, Validation, Visualization, Writing – review & editing

  Current address: Alloy Therapeutics, Waltham, Massachusetts, United States of America

  Affiliation Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York, United States of America

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• Frederick W. Holtsberg,

  Roles Data curation, Formal analysis, Investigation, Methodology, Resources, Validation, Visualization, Writing – review & editing

  Current address: AbVacc Inc., Rockville, Maryland, United States of America

  Affiliation Integrated BioTherapeutics, Inc., Rockville, Maryland, United States of America

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• Sergey Shulenin,

  Roles Data curation, Formal analysis, Investigation, Methodology, Resources, Validation, Visualization, Writing – review & editing

  Affiliation Integrated BioTherapeutics, Inc., Rockville, Maryland, United States of America

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• Zachary A. Bornholdt,

  Roles Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – review & editing

  Current address: Eitr Biologics, San Diego, California, United States of America

  Affiliation Mapp Biopharmaceutical Inc., San Diego, California, United States of America

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• M. Javad Aman,

  Roles Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – review & editing

  Current address: AbVacc Inc., Rockville, Maryland, United States of America

  Affiliation Integrated BioTherapeutics, Inc., Rockville, Maryland, United States of America

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• Anna N. Honko,

  Roles Data curation, Formal analysis, Investigation, Methodology, Resources, Validation, Visualization, Writing – review & editing

  Affiliation Department of Virology, Immunology, and Microbiology; and National Emerging Infectious Diseases Laboratories, Boston University School of Medicine, Boston, Massachusetts, United States of America

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• Anthony Griffiths,

  Roles Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – review & editing

  Affiliation Department of Virology, Immunology, and Microbiology; and National Emerging Infectious Diseases Laboratories, Boston University School of Medicine, Boston, Massachusetts, United States of America

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• John M. Dye,

  Roles Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – review & editing

  Affiliation Virology Division, United States Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America

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• Kartik Chandran ,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: andrew.s.herbert4.civ@health.mil (ASH); kartik.chandran@einsteinmed.edu (KC); jon.lai@einsteinmed.edu (JRL)

  Affiliation Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, New York, United States of America

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•  [ ... ],
• Jonathan R. Lai

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: andrew.s.herbert4.civ@health.mil (ASH); kartik.chandran@einsteinmed.edu (KC); jon.lai@einsteinmed.edu (JRL)

  Affiliation Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York, United States of America

  https://orcid.org/0000-0002-4863-0015

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