The T4bSS of Legionella features a two-step secretion pathway with an inner membrane intermediate for secretion of transmembrane effectors

• Silke Malmsheimer,

  Roles Conceptualization, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing

  Current address: Institut de Recherche en Infectiologie de Montpellier, Equipe Kremer, UMR 9004 –CNRS / UM, Montpellier, France

  Affiliation University of Tübingen, Interfaculty Institute of Microbiology and Infection Medicine (IMIT), Section of Cellular and Molecular Microbiology, Tübingen, Germany

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• Iwan Grin,

  Roles Methodology, Supervision

  Affiliation University of Tübingen, Interfaculty Institute of Microbiology and Infection Medicine (IMIT), Section of Cellular and Molecular Microbiology, Tübingen, Germany

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• Erwin Bohn,

  Roles Methodology, Writing – original draft

  Affiliation University of Tübingen, Interfaculty Institute of Microbiology and Infection Medicine (IMIT), Institute of Medical Microbiology and Hygiene, Tübingen, Germany

  https://orcid.org/0000-0003-0780-862X

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• Mirita Franz-Wachtel,

  Roles Formal analysis, Methodology, Writing – original draft

  Affiliation University of Tübingen, Proteome Center Tübingen, Tübingen, Germany

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• Boris Macek,

  Roles Methodology

  Affiliation University of Tübingen, Proteome Center Tübingen, Tübingen, Germany

  https://orcid.org/0000-0001-7876-7736

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• Tobias Sahr,

  Roles Methodology, Supervision

  Affiliation Institute Pasteur, Université Paris Cité, Biologie des Bactéries Intracellulaires, Paris, France

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• Fabian Smollich,

  Roles Investigation

  Affiliation University of Tübingen, Interfaculty Institute of Microbiology and Infection Medicine (IMIT), Section of Cellular and Molecular Microbiology, Tübingen, Germany

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• David Chetrit,

  Roles Methodology, Supervision

  Affiliation Yale University, Department of Microbial Pathogenesis, New Haven, Connecticut, United States of America

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• Amit Meir,

  Roles Methodology, Supervision

  Current address: University of Glasgow, MRC Centre for Virus Research, School of Infection and Immunity, Glasgow, United Kingdom

  Affiliations Yale University, Department of Microbial Pathogenesis, New Haven, Connecticut, United States of America, Birkbeck Institute of Structural and Molecular Biology, Birkbeck and UCL, London, United Kingdom

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• Craig Roy,

  Roles Funding acquisition, Methodology

  Affiliation Yale University, Department of Microbial Pathogenesis, New Haven, Connecticut, United States of America

  https://orcid.org/0000-0003-4490-440X

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• Carmen Buchrieser,

  Roles Funding acquisition, Methodology, Supervision

  Affiliation Institute Pasteur, Université Paris Cité, Biologie des Bactéries Intracellulaires, Paris, France

  https://orcid.org/0000-0003-3477-9190

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• Samuel Wagner

  Roles Conceptualization, Funding acquisition, Supervision, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: samuel.wagner@med.uni-tuebingen.de

  Affiliations University of Tübingen, Interfaculty Institute of Microbiology and Infection Medicine (IMIT), Section of Cellular and Molecular Microbiology, Tübingen, Germany, Excellence Cluster "Controlling Microbes to Fight Infections" (CMFI), Tübingen, Germany, German Center for Infection Research (DZIF), partner-site Tübingen, Tübingen, Germany

  https://orcid.org/0000-0003-1808-3556

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