Autoimmunity-associated allele of tyrosine phosphatase gene PTPN22 enhances anti-viral immunity

Robin C. Orozco; Kristi Marquardt; Isaraphorn Pratumchai; Anam Fatima Shaikh; Kerri Mowen; Alain Domissy; John R. Teijaro; Linda A. Sherman

doi:10.1371/journal.ppat.1012095

Loading metrics

Open Access

Peer-reviewed

Research Article

Autoimmunity-associated allele of tyrosine phosphatase gene PTPN22 enhances anti-viral immunity

Robin C. Orozco ,

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Methodology, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

* E-mail: Orozco.robin@ku.edu (RCO); lsherman@scripps.edu (LAS)

Affiliations Department of Immunology and Microbiology, Scripps Research, La Jolla, California, United States of America, Department of Molecular Biosciences, University of Kansas, Lawrence, Kansas, United States of America

https://orcid.org/0000-0002-2138-2912

⨯
Kristi Marquardt,

Roles Data curation, Formal analysis, Methodology

Affiliation Department of Immunology and Microbiology, Scripps Research, La Jolla, California, United States of America
⨯
Isaraphorn Pratumchai,

Roles Data curation, Formal analysis, Methodology

Affiliation Department of Immunology and Microbiology, Scripps Research, La Jolla, California, United States of America
⨯
Anam Fatima Shaikh,

Roles Data curation, Formal analysis, Methodology

Affiliation Department of Molecular Biosciences, University of Kansas, Lawrence, Kansas, United States of America
⨯
Kerri Mowen †,

† Deceased.

Roles Resources

Affiliation Department of Immunology and Microbiology, Scripps Research, La Jolla, California, United States of America
⨯
Alain Domissy,

Roles Data curation, Formal analysis, Methodology, Writing – review & editing

Affiliation Genomics Core, Scripps Research, La Jolla, California, United States of America
⨯
John R. Teijaro,

Roles Conceptualization, Resources, Supervision, Writing – review & editing

Affiliation Department of Immunology and Microbiology, Scripps Research, La Jolla, California, United States of America
⨯
Linda A. Sherman

Roles Conceptualization, Funding acquisition, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

* E-mail: Orozco.robin@ku.edu (RCO); lsherman@scripps.edu (LAS)

Affiliation Department of Immunology and Microbiology, Scripps Research, La Jolla, California, United States of America
⨯

Autoimmunity-associated allele of tyrosine phosphatase gene PTPN22 enhances anti-viral immunity

Robin C. Orozco,
Kristi Marquardt,
Isaraphorn Pratumchai,
Anam Fatima Shaikh,
Kerri Mowen,
Alain Domissy,
John R. Teijaro,
Linda A. Sherman

Published: March 21, 2024
https://doi.org/10.1371/journal.ppat.1012095

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

T helper cells
Is the Subject Area "T helper cells" applicable to this article?

Thanks for your feedback.
Cytotoxic T cells
Is the Subject Area "Cytotoxic T cells" applicable to this article?

Thanks for your feedback.
Cloning
Is the Subject Area "Cloning" applicable to this article?

Thanks for your feedback.
Bone marrow cells
Is the Subject Area "Bone marrow cells" applicable to this article?

Thanks for your feedback.
Immune cells
Is the Subject Area "Immune cells" applicable to this article?

Thanks for your feedback.
Antiviral immune response
Is the Subject Area "Antiviral immune response" applicable to this article?

Thanks for your feedback.
Gene expression
Is the Subject Area "Gene expression" applicable to this article?

Thanks for your feedback.
Lymphocytes
Is the Subject Area "Lymphocytes" applicable to this article?

Thanks for your feedback.