Computationally inferred cell-type specific epigenome-wide DNA methylation analysis unveils distinct methylation patterns among immune cells for HIV infection in three cohorts

• Xinyu Zhang,

  Roles Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

  Affiliations Department of Psychiatry, Yale School of Medicine, New Haven, Connecticut, United States of America, VA Connecticut Healthcare System, West Haven, Connecticut, United States of America

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• Ying Hu,

  Roles Conceptualization, Formal analysis, Methodology, Supervision, Writing – review & editing

  Affiliation Center for Biomedical Information and Information Technology, National Cancer Institute, Rockville, Maryland, United States of America

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• Ral E. Vandenhoudt,

  Roles Investigation, Visualization, Writing – review & editing

  Affiliations Department of Psychiatry, Yale School of Medicine, New Haven, Connecticut, United States of America, VA Connecticut Healthcare System, West Haven, Connecticut, United States of America

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• Chunhua Yan,

  Roles Supervision, Writing – review & editing

  Affiliation Center for Biomedical Information and Information Technology, National Cancer Institute, Rockville, Maryland, United States of America

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• Vincent C. Marconi,

  Roles Conceptualization, Resources, Supervision, Writing – review & editing

  Affiliations Division of Infectious Diseases, Emory University School of Medicine and Department of Global Health, Rollins School of Public Health, Emory University, Georgia, United States of America, Atlanta Veterans Affairs Healthcare System, Decatur, Georgia, United States of America

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• Mardge H. Cohen,

  Roles Data curation, Resources, Writing – review & editing

  Affiliation Department of Medicine, Stroger Hospital of Cook County, Chicago, Illinois, United States of America

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• Zuoheng Wang,

  Roles Conceptualization, Methodology, Supervision, Writing – review & editing

  Affiliation Department of Biostatistics, Yale School of Public Health, New Haven, Connecticut, United States of America

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• Amy C. Justice,

  Roles Conceptualization, Data curation, Investigation, Resources, Supervision, Writing – review & editing

  Affiliations VA Connecticut Healthcare System, West Haven, Connecticut, United States of America, Department of Biostatistics, Yale School of Public Health, New Haven, Connecticut, United States of America, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut, United States of America

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• Bradley E. Aouizerat ,

  Contributed equally to this work with: Bradley E. Aouizerat, Ke Xu

  Roles Conceptualization, Data curation, Funding acquisition, Investigation, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: bea4@nyu.edu (BEA); ke.xu@yale.edu (KX)

  Affiliations Translational Research Center, College of Dentistry, New York University, New York, New York, United States of America, Department of Oral and Maxillofacial Surgery, College of Dentistry, New York University, New York, New York, United States of America

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• Ke Xu

  Contributed equally to this work with: Bradley E. Aouizerat, Ke Xu

  Roles Conceptualization, Data curation, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Validation, Writing – original draft, Writing – review & editing

  * E-mail: bea4@nyu.edu (BEA); ke.xu@yale.edu (KX)

  Affiliations Department of Psychiatry, Yale School of Medicine, New Haven, Connecticut, United States of America, VA Connecticut Healthcare System, West Haven, Connecticut, United States of America, Biomedical Informatics and Data Science, Yale School of Medicine, New Haven, Connecticut, United States of America

  https://orcid.org/0000-0002-6472-7052

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