Downregulation of CPSF6 leads to global mRNA 3’ UTR shortening and enhanced antiviral immune responses

• Yong Ge,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Guangdong Province Key Laboratory of Pharmaceutical Functional Genes, MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University, Guangzhou, China, Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Zhuhai, China

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• Jingrong Huang,

  Roles Data curation, Formal analysis, Investigation, Methodology, Visualization

  Affiliations Guangdong Province Key Laboratory of Pharmaceutical Functional Genes, MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University, Guangzhou, China, Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Zhuhai, China

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• Rong Chen,

  Roles Data curation, Formal analysis, Investigation, Methodology, Visualization

  Affiliations Guangdong Province Key Laboratory of Pharmaceutical Functional Genes, MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University, Guangzhou, China, Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Zhuhai, China

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• Yonggui Fu,

  Roles Methodology

  Affiliation Guangdong Province Key Laboratory of Pharmaceutical Functional Genes, MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University, Guangzhou, China

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• Tao Ling,

  Roles Investigation, Methodology

  Affiliations Guangdong Province Key Laboratory of Pharmaceutical Functional Genes, MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University, Guangzhou, China, Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Zhuhai, China

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• Xin Ou,

  Roles Investigation, Methodology

  Affiliation Guangdong Province Key Laboratory of Pharmaceutical Functional Genes, MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University, Guangzhou, China

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• Xiaohui Rong,

  Roles Investigation

  Affiliations Guangdong Province Key Laboratory of Pharmaceutical Functional Genes, MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University, Guangzhou, China, Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Zhuhai, China

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• Youxiang Cheng,

  Roles Investigation

  Affiliations Guangdong Province Key Laboratory of Pharmaceutical Functional Genes, MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University, Guangzhou, China, Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Zhuhai, China

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• Yi Lin,

  Roles Investigation

  Affiliations Guangdong Province Key Laboratory of Pharmaceutical Functional Genes, MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University, Guangzhou, China, Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Zhuhai, China

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• Fengyi Zhou,

  Roles Investigation

  Affiliation Guangdong Province Key Laboratory of Pharmaceutical Functional Genes, MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University, Guangzhou, China

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• Chuanjian Lu,

  Roles Writing – review & editing

  Affiliations The Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou, China, State Key Laboratory of Dampness Syndrome of Chinese Medicine, Guangdong-Hong Kong-Macau Joint Lab on Chinese Medicine and Immune Disease Research, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangdong Provincial Academy of Chinese Medical Sciences, Guangzhou, China

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• Shaochun Yuan ,

  Roles Conceptualization, Funding acquisition, Project administration, Supervision, Validation, Writing – original draft, Writing – review & editing

  * E-mail: yuanshch@mail.sysu.edu.cn (SY); lssxal@mail.sysu.edu.cn (AX)

  Affiliations Guangdong Province Key Laboratory of Pharmaceutical Functional Genes, MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University, Guangzhou, China, Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Zhuhai, China

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• Anlong Xu

  Roles Conceptualization, Funding acquisition, Project administration, Supervision, Validation, Writing – review & editing

  * E-mail: yuanshch@mail.sysu.edu.cn (SY); lssxal@mail.sysu.edu.cn (AX)

  Affiliations Guangdong Province Key Laboratory of Pharmaceutical Functional Genes, MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University, Guangzhou, China, School of Life Sciences, Beijing University of Chinese Medicine, Beijing, China

  https://orcid.org/0000-0002-1419-3494

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