Amino acid 138 in the HA of a H3N2 subtype influenza A virus increases affinity for the lower respiratory tract and alveolar macrophages in pigs

• Matias Cardenas,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Writing – original draft, Writing – review & editing

  Affiliation Department of Population Health, College of Veterinary Medicine, University of Georgia, Athens, Georgia, United States of America

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• Brittany Seibert,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Department of Population Health, College of Veterinary Medicine, University of Georgia, Athens, Georgia, United States of America

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• Brianna Cowan,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Department of Population Health, College of Veterinary Medicine, University of Georgia, Athens, Georgia, United States of America

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• Ana Luiza S. Fraiha,

  Roles Investigation, Methodology, Writing – review & editing

  Current address: Departamento de Medicina Veterinária Preventiva, Escola de Veterinária, Universidade Federal de Minas Gerais, Minas Gerais, Brazil

  Affiliation Department of Population Health, College of Veterinary Medicine, University of Georgia, Athens, Georgia, United States of America

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• Silvia Carnaccini,

  Roles Formal analysis, Investigation, Methodology, Writing – review & editing

  Affiliation Department of Population Health, College of Veterinary Medicine, University of Georgia, Athens, Georgia, United States of America

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• L. Claire Gay,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Department of Population Health, College of Veterinary Medicine, University of Georgia, Athens, Georgia, United States of America

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• Flavio Cargnin Faccin,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Department of Population Health, College of Veterinary Medicine, University of Georgia, Athens, Georgia, United States of America

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• C. Joaquin Caceres,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Department of Population Health, College of Veterinary Medicine, University of Georgia, Athens, Georgia, United States of America

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• Tavis K. Anderson,

  Roles Funding acquisition, Project administration, Writing – review & editing

  Affiliation Virus and Prion Research Unit, National Animal Disease Center, United States Department of Agriculture, Agricultural Research Service, Ames, Iowa, United States of America

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• Amy L. Vincent Baker,

  Roles Funding acquisition, Project administration, Writing – review & editing

  Affiliation Virus and Prion Research Unit, National Animal Disease Center, United States Department of Agriculture, Agricultural Research Service, Ames, Iowa, United States of America

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• Daniel R. Perez,

  Roles Funding acquisition, Project administration, Supervision, Writing – review & editing

  Affiliation Department of Population Health, College of Veterinary Medicine, University of Georgia, Athens, Georgia, United States of America

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• Daniela S. Rajao

  Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: daniela.rajao@uga.edu

  Affiliation Department of Population Health, College of Veterinary Medicine, University of Georgia, Athens, Georgia, United States of America

  https://orcid.org/0000-0002-0772-0065

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