Caspase-1 in Cx3cr1-expressing cells drives an IL-18-dependent T cell response that promotes parasite control during acute Toxoplasma gondii infection

• Isaac W. Babcock,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Center for Brain Immunology and Glia, Department of Neuroscience, University of Virginia, Charlottesville, Virginia, United States of America

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• Lydia A. Sibley,

  Roles Investigation, Writing – review & editing

  Affiliation Center for Brain Immunology and Glia, Department of Neuroscience, University of Virginia, Charlottesville, Virginia, United States of America

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• Sydney A. Labuzan,

  Roles Writing – review & editing

  Affiliation Center for Brain Immunology and Glia, Department of Neuroscience, University of Virginia, Charlottesville, Virginia, United States of America

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• Maureen N. Cowan,

  Roles Formal analysis, Methodology, Visualization

  Affiliation Center for Brain Immunology and Glia, Department of Neuroscience, University of Virginia, Charlottesville, Virginia, United States of America

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• Ish Sethi,

  Roles Data curation, Investigation

  Affiliation Center for Brain Immunology and Glia, Department of Neuroscience, University of Virginia, Charlottesville, Virginia, United States of America

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• Seblework Alemu,

  Roles Formal analysis, Investigation, Methodology

  Affiliation Center for Brain Immunology and Glia, Department of Neuroscience, University of Virginia, Charlottesville, Virginia, United States of America

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• Abigail G. Kelly,

  Roles Writing – review & editing

  Affiliation Center for Brain Immunology and Glia, Department of Neuroscience, University of Virginia, Charlottesville, Virginia, United States of America

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• Michael A. Kovacs,

  Roles Conceptualization

  Affiliation Center for Brain Immunology and Glia, Department of Neuroscience, University of Virginia, Charlottesville, Virginia, United States of America

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• John R. Lukens,

  Roles Resources, Writing – review & editing

  Affiliation Center for Brain Immunology and Glia, Department of Neuroscience, University of Virginia, Charlottesville, Virginia, United States of America

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• Tajie H. Harris

  Roles Conceptualization, Funding acquisition, Project administration, Resources, Supervision, Writing – review & editing

  * E-mail: tajieharris@virginia.edu

  Affiliation Center for Brain Immunology and Glia, Department of Neuroscience, University of Virginia, Charlottesville, Virginia, United States of America

  https://orcid.org/0000-0002-1355-2109

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