Unmutated but T cell dependent IgM antibodies targeting Streptococcus suis play an essential role in bacterial clearance

• Dominic Dolbec,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Research Group on Infectious Diseases in Production Animals (GREMIP) and Swine and Poultry Infectious Diseases Research Center (CRIPA), Department of Pathology and Microbiology, Faculty of Veterinary Medicine, University of Montreal, Saint-Hyacinthe, Quebec, Canada

  ⨯
• Mélanie Lehoux,

  Roles Investigation, Methodology

  Affiliation Research Group on Infectious Diseases in Production Animals (GREMIP) and Swine and Poultry Infectious Diseases Research Center (CRIPA), Department of Pathology and Microbiology, Faculty of Veterinary Medicine, University of Montreal, Saint-Hyacinthe, Quebec, Canada

  ⨯
• Alexis Asselin de Beauville,

  Roles Investigation

  Affiliation Research Group on Infectious Diseases in Production Animals (GREMIP) and Swine and Poultry Infectious Diseases Research Center (CRIPA), Department of Pathology and Microbiology, Faculty of Veterinary Medicine, University of Montreal, Saint-Hyacinthe, Quebec, Canada

  ⨯
• Astrid Zahn,

  Roles Conceptualization, Methodology

  Affiliation Institut de Recherches Cliniques de Montréal, Center for Immunity, Inflammation and Infectious Diseases, Quebec, Canada

  ⨯
• Javier Marcelo Di Noia ,

  Roles Conceptualization, Funding acquisition, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: Javier.Di.Noia@ircm.qc.ca (JMDN); Mariela.Segura@umontreal.ca (MS)

  Affiliations Institut de Recherches Cliniques de Montréal, Center for Immunity, Inflammation and Infectious Diseases, Quebec, Canada, Department of Medicine, Faculty of Sciences, University of Montreal, Montreal, Quebec, Canada

  ⨯
• Mariela Segura

  Roles Conceptualization, Funding acquisition, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: Javier.Di.Noia@ircm.qc.ca (JMDN); Mariela.Segura@umontreal.ca (MS)

  Affiliation Research Group on Infectious Diseases in Production Animals (GREMIP) and Swine and Poultry Infectious Diseases Research Center (CRIPA), Department of Pathology and Microbiology, Faculty of Veterinary Medicine, University of Montreal, Saint-Hyacinthe, Quebec, Canada

  https://orcid.org/0000-0002-7489-4882

  ⨯