Pseudomonas aeruginosa two-component system CprRS regulates HigBA expression and bacterial cytotoxicity in response to LL-37 stress

Yingjie Song; Siping Zhang; Ninglin Zhao; Cheng Nong; Yongxing He; Rui Bao

doi:10.1371/journal.ppat.1011946

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Open Access

Peer-reviewed

Research Article

Pseudomonas aeruginosa two-component system CprRS regulates HigBA expression and bacterial cytotoxicity in response to LL-37 stress

Yingjie Song ,

Contributed equally to this work with: Yingjie Song, Siping Zhang, Ninglin Zhao

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing – original draft

Affiliation College of Life Science, Sichuan Normal University, Chengdu, China
⨯
Siping Zhang ,

Contributed equally to this work with: Yingjie Song, Siping Zhang, Ninglin Zhao

Roles Data curation, Formal analysis, Investigation, Resources, Software, Validation, Visualization

Affiliation Ministry of Education Key Laboratory of Cell Activities and Stress Adaptations, School of Life Sciences, Lanzhou University, Lanzhou, China
⨯
Ninglin Zhao ,

Contributed equally to this work with: Yingjie Song, Siping Zhang, Ninglin Zhao

Roles Data curation, Investigation, Visualization

Affiliation Center of Infectious Diseases, Division of Infectious Diseases in State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, China
⨯
Cheng Nong,

Roles Data curation, Investigation

Affiliation Center of Infectious Diseases, Division of Infectious Diseases in State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, China
⨯
Yongxing He ,

Roles Investigation, Resources, Supervision, Writing – review & editing

* E-mail: baorui@scu.edu.cn (R.B); heyx@lzu.edu.cn (Y.-X.H)

Affiliation Ministry of Education Key Laboratory of Cell Activities and Stress Adaptations, School of Life Sciences, Lanzhou University, Lanzhou, China
⨯
Rui Bao

Roles Conceptualization, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Supervision, Writing – review & editing

* E-mail: baorui@scu.edu.cn (R.B); heyx@lzu.edu.cn (Y.-X.H)

Affiliation Center of Infectious Diseases, Division of Infectious Diseases in State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, China

https://orcid.org/0000-0002-6083-8716

⨯

Pseudomonas aeruginosa two-component system CprRS regulates HigBA expression and bacterial cytotoxicity in response to LL-37 stress

Yingjie Song,
Siping Zhang,
Ninglin Zhao,
Cheng Nong,
Yongxing He,
Rui Bao

Published: January 10, 2024
https://doi.org/10.1371/journal.ppat.1011946

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Pseudomonas aeruginosa
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DNA-binding proteins
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