N123I mutation in the ALV-J receptor-binding domain region enhances viral replication ability by increasing the binding affinity with chNHE1

• Mengmeng Yu ,

  Contributed equally to this work with: Mengmeng Yu, Yao Zhang

  Roles Data curation, Formal analysis, Investigation, Methodology, Resources, Software, Visualization, Writing – original draft

  Affiliation Avian Immunosuppressive Diseases Division, State Key Laboratory for Animal Disease Control and Prevention, Harbin Veterinary Research Institute, the Chinese Academy of Agricultural Sciences, Harbin, China

  ⨯
• Yao Zhang ,

  Contributed equally to this work with: Mengmeng Yu, Yao Zhang

  Roles Data curation, Formal analysis, Investigation, Methodology, Resources, Software, Visualization

  Affiliation Avian Immunosuppressive Diseases Division, State Key Laboratory for Animal Disease Control and Prevention, Harbin Veterinary Research Institute, the Chinese Academy of Agricultural Sciences, Harbin, China

  ⨯
• Li Zhang,

  Roles Investigation, Methodology, Resources, Software

  Affiliation Avian Immunosuppressive Diseases Division, State Key Laboratory for Animal Disease Control and Prevention, Harbin Veterinary Research Institute, the Chinese Academy of Agricultural Sciences, Harbin, China

  ⨯
• Suyan Wang,

  Roles Funding acquisition, Investigation, Methodology, Writing – review & editing

  Affiliation Avian Immunosuppressive Diseases Division, State Key Laboratory for Animal Disease Control and Prevention, Harbin Veterinary Research Institute, the Chinese Academy of Agricultural Sciences, Harbin, China

  ⨯
• Yongzhen Liu,

  Roles Methodology, Resources, Writing – review & editing

  Affiliation Avian Immunosuppressive Diseases Division, State Key Laboratory for Animal Disease Control and Prevention, Harbin Veterinary Research Institute, the Chinese Academy of Agricultural Sciences, Harbin, China

  ⨯
• Zhuangzhuang Xu,

  Roles Investigation, Methodology, Resources

  Affiliation Avian Immunosuppressive Diseases Division, State Key Laboratory for Animal Disease Control and Prevention, Harbin Veterinary Research Institute, the Chinese Academy of Agricultural Sciences, Harbin, China

  ⨯
• Peng Liu,

  Roles Methodology, Resources, Validation

  Affiliation Avian Immunosuppressive Diseases Division, State Key Laboratory for Animal Disease Control and Prevention, Harbin Veterinary Research Institute, the Chinese Academy of Agricultural Sciences, Harbin, China

  ⨯
• Yuntong Chen,

  Roles Methodology, Validation

  Affiliation Avian Immunosuppressive Diseases Division, State Key Laboratory for Animal Disease Control and Prevention, Harbin Veterinary Research Institute, the Chinese Academy of Agricultural Sciences, Harbin, China

  ⨯
• Ru Guo,

  Roles Methodology, Software

  Affiliation Avian Immunosuppressive Diseases Division, State Key Laboratory for Animal Disease Control and Prevention, Harbin Veterinary Research Institute, the Chinese Academy of Agricultural Sciences, Harbin, China

  ⨯
• Lingzhai Meng,

  Roles Resources

  Affiliation Avian Immunosuppressive Diseases Division, State Key Laboratory for Animal Disease Control and Prevention, Harbin Veterinary Research Institute, the Chinese Academy of Agricultural Sciences, Harbin, China

  ⨯
• Tao Zhang,

  Roles Resources

  Affiliation Avian Immunosuppressive Diseases Division, State Key Laboratory for Animal Disease Control and Prevention, Harbin Veterinary Research Institute, the Chinese Academy of Agricultural Sciences, Harbin, China

  ⨯
• Wenrui Fan,

  Roles Resources

  Affiliation Avian Immunosuppressive Diseases Division, State Key Laboratory for Animal Disease Control and Prevention, Harbin Veterinary Research Institute, the Chinese Academy of Agricultural Sciences, Harbin, China

  ⨯
• Xiaole Qi,

  Roles Methodology

  Affiliation Avian Immunosuppressive Diseases Division, State Key Laboratory for Animal Disease Control and Prevention, Harbin Veterinary Research Institute, the Chinese Academy of Agricultural Sciences, Harbin, China

  ⨯
• Li Gao,

  Roles Methodology

  Affiliation Avian Immunosuppressive Diseases Division, State Key Laboratory for Animal Disease Control and Prevention, Harbin Veterinary Research Institute, the Chinese Academy of Agricultural Sciences, Harbin, China

  ⨯
• Yanping Zhang,

  Roles Methodology

  Affiliation Avian Immunosuppressive Diseases Division, State Key Laboratory for Animal Disease Control and Prevention, Harbin Veterinary Research Institute, the Chinese Academy of Agricultural Sciences, Harbin, China

  ⨯
• Hongyu Cui,

  Roles Methodology

  Affiliation Avian Immunosuppressive Diseases Division, State Key Laboratory for Animal Disease Control and Prevention, Harbin Veterinary Research Institute, the Chinese Academy of Agricultural Sciences, Harbin, China

  ⨯
•  [ ... ],
• Yulong Gao

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: gaoyulong@caas.cn

  Affiliations Avian Immunosuppressive Diseases Division, State Key Laboratory for Animal Disease Control and Prevention, Harbin Veterinary Research Institute, the Chinese Academy of Agricultural Sciences, Harbin, China, Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Disease and Zoonoses, Yangzhou, China, National Poultry Laboratory Animal Resource Center, Harbin, China

  https://orcid.org/0000-0002-0448-8467

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