Kaposi’s sarcoma herpesvirus latency-associated nuclear antigen broadly regulates viral gene expression and is essential for lytic infection

• Shijun Li,

  Roles Conceptualization, Formal analysis, Investigation, Project administration, Validation, Writing – original draft, Writing – review & editing

  Affiliations Departments of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, United States of America, Program in Virology, Harvard Medical School, Boston, Massachusetts, United States of America

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• Mengbo Wang,

  Roles Formal analysis, Visualization

  Affiliation Department of Computer Science, Purdue University, West Lafayette, Indiana

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• Nicholas Van Sciver,

  Roles Formal analysis, Investigation, Validation

  Affiliations Departments of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, United States of America, Program in Virology, Harvard Medical School, Boston, Massachusetts, United States of America

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• Agnieszka Szymula,

  Roles Formal analysis, Investigation, Validation

  Affiliations Departments of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, United States of America, Program in Virology, Harvard Medical School, Boston, Massachusetts, United States of America

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• Vinayak Sadasivam Tumuluri,

  Roles Formal analysis, Investigation, Validation

  Affiliations Departments of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, United States of America, Program in Virology, Harvard Medical School, Boston, Massachusetts, United States of America

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• Athira George,

  Roles Formal analysis, Writing – review & editing

  Affiliations Departments of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, United States of America, Program in Virology, Harvard Medical School, Boston, Massachusetts, United States of America

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• Akshaya Ramachandran,

  Roles Formal analysis

  Affiliations Departments of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, United States of America, Program in Virology, Harvard Medical School, Boston, Massachusetts, United States of America

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• Komal Raina,

  Roles Formal analysis, Writing – review & editing

  Affiliations Departments of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, United States of America, Program in Virology, Harvard Medical School, Boston, Massachusetts, United States of America

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• Catarina N. Costa,

  Roles Formal analysis

  Affiliations Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Avenida Professor Egas Moniz, Lisboa, Portugal, Universidade Católica Portuguesa, Católica Medical School, Católica Biomedical Research, Palma de Cima, Portugal

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• Bo Zhao,

  Roles Formal analysis, Supervision

  Affiliation Departments of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, United States of America

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• Majid Kazemian,

  Roles Formal analysis, Funding acquisition, Supervision, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Department of Computer Science, Purdue University, West Lafayette, Indiana, Department of Biochemistry, Purdue University, West Lafayette, Indiana

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• J. Pedro Simas ,

  Roles Formal analysis, Funding acquisition, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: psimas@ucp.pt (JPS); kkaye@bwh.harvard.edu (KMK)

  Affiliations Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Avenida Professor Egas Moniz, Lisboa, Portugal, Universidade Católica Portuguesa, Católica Medical School, Católica Biomedical Research, Palma de Cima, Portugal

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• Kenneth M. Kaye

  Roles Conceptualization, Formal analysis, Funding acquisition, Project administration, Supervision, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: psimas@ucp.pt (JPS); kkaye@bwh.harvard.edu (KMK)

  Affiliations Departments of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, United States of America, Program in Virology, Harvard Medical School, Boston, Massachusetts, United States of America, Broad Institute of Harvard University and Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

  https://orcid.org/0000-0001-5802-4556

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